Striatal Nurr1, but not FosB expression links a levodopa-induced dyskinesia phenotype to genotype in Fisher 344 vs. Lewis hemiparkinsonian rats
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2020.113327
Abstract: Numerous genes, and alterations in their expression, have been identified as risk factors for developing levodopa-induced dyskinesia (LID). However, our understanding of the complexities of molecular changes remains insufficient for development of clinical treatment. In… read more here.
Keywords: levodopa induced; fosb; expression; dyskinesia ... See more keywords
Influence of Water on Amorphous Lidocaine.
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DOI: 10.1021/acs.molpharmaceut.2c00339
Abstract: Water is generally regarded as a universal plasticizer of amorphous drugs or amorphous drug-containing systems. A decrease in glass-transition temperature (Tg) is considered the general result of this plasticizing effect. A recent study exhibits that… read more here.
Keywords: plasticizing effect; water; influence water; lid ... See more keywords