How does early‐life adversity shape telomere dynamics during adulthood? Problems and paradigms
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DOI: 10.1002/bies.202100184
Abstract: Although early‐life adversity has been associated with negative consequences during adulthood, growing evidence shows that such adversity can also lead to subsequent stress resilience and positive fitness outcomes. Telomere dynamics are relevant in this context… read more here.
Keywords: early life; life adversity; telomere dynamics; adult telomere ... See more keywords
The involvement of astrocytes in early‐life adversity induced programming of the brain
Sign Up to like & getrecommendations! Published in 2019 at "Glia"
DOI: 10.1002/glia.23625
Abstract: Early‐life adversity (ELA) in the form of stress, inflammation, or malnutrition, can increase the risk of developing psychopathology or cognitive problems in adulthood. The neurobiological substrates underlying this process remain unclear. While neuronal dysfunction and… read more here.
Keywords: life adversity; brain; early life; astrocytes early ... See more keywords
Early life adversity in dogs produces altered physiological and behavioral responses during a social stress-buffering paradigm.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the experimental analysis of behavior"
DOI: 10.1002/jeab.856
Abstract: Although owners can act as stress buffers for their dogs, whether dogs with poor early life histories with humans will respond similarly is unknown. We tested 45 dogs, 23 of which were rescued from adverse… read more here.
Keywords: adversity dogs; early life; life adversity; dogs adverse ... See more keywords
Effects of early life adversity on maternal effort and glucocorticoids in wild olive baboons
Sign Up to like & getrecommendations! Published in 2021 at "Behavioral Ecology and Sociobiology"
DOI: 10.1007/s00265-021-03056-7
Abstract: Adverse experiences during early life exert important effects on development, health, reproduction, and social bonds, with consequences often persisting across generations. A mother’s early life experiences can impact her offspring’s development through a number of… read more here.
Keywords: life adversity; life; early life; maternal effort ... See more keywords
Negative consequences of early-life adversity on substance use as mediated by corticotropin-releasing factor modulation of serotonin activity
Sign Up to like & getrecommendations! Published in 2018 at "Neurobiology of Stress"
DOI: 10.1016/j.ynstr.2018.08.001
Abstract: Early-life adversity is associated with increased risk for substance abuse in later life, with women more likely to report past and current stress as a mediating factor in their substance use and relapse as compared… read more here.
Keywords: substance; life; early life; life adversity ... See more keywords
Early life adversity, inflammation, and immune function: An initial test of adaptive response models of immunological programming
Sign Up to like & getrecommendations! Published in 2022 at "Development and Psychopathology"
DOI: 10.1017/s095457942100170x
Abstract: Abstract Much research indicates that exposure to early life adversity (ELA) predicts chronic inflammatory activity, increasing one’s risk of developing diseases of aging later in life. Despite its costs, researchers have proposed that chronic inflammation… read more here.
Keywords: inflammation; early life; inflammation immune; life adversity ... See more keywords
Early Life Adversity and Blunted Cardiovascular Reactivity to Acute Psychological Stress: The Role of Current Depressive Symptoms
Sign Up to like & getrecommendations! Published in 2021 at "Psychosomatic Medicine"
DOI: 10.1097/psy.0000000000001024
Abstract: ABSTRACT Objective The pathways underlying the early life adversity and cardiovascular reactivity association remain unclear. The current study examined the role of current depressive symptoms on this relationship. Methods Mediation analyses were conducted using data… read more here.
Keywords: early life; current depressive; life adversity; cardiovascular reactivity ... See more keywords
The effects of early life adversity on growth, maturation, and steroid hormones in male and female rats
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Neuroscience"
DOI: 10.1111/ejn.14609
Abstract: Early life adversity is a risk factor for psychiatric disorders, yet the mechanisms by which adversity increases this risk are still being delineated. Here, we used a limited bedding and nesting (LBN) manipulation in rats… read more here.
Keywords: life; early life; effects early; life adversity ... See more keywords
The inferior frontal gyrus spontaneous activity mediates the association of early life adversity with self-control ability in late adolescents.
Sign Up to like & getrecommendations! Published in 2023 at "Psychophysiology"
DOI: 10.1111/psyp.14291
Abstract: Self-control, the ability to regulate prepotent desires or impulses in order to realize one's valued goal, has been found to be associated with early life adversity. However, the neural correlates underlying this relationship remain poorly… read more here.
Keywords: control ability; self control; life adversity; early life ... See more keywords
Epigenetics of early-life adversity in youth: cross-sectional and longitudinal associations
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DOI: 10.1186/s13148-022-01269-9
Abstract: Background Altered DNA methylation (DNAm) may be one pathway through which early-life adversity (ELA) contributes to adverse mental and physical health outcomes. This study investigated whether the presence versus absence of ELA experiences reflecting the… read more here.
Keywords: coefficient; early life; life adversity; cross sectional ... See more keywords
Early-life adversity and long-term neurobehavioral outcomes: epigenome as a bridge?
Sign Up to like & getrecommendations! Published in 2017 at "Human Genomics"
DOI: 10.1186/s40246-017-0129-z
Abstract: Accumulating evidence suggests that adversities at critical periods in early life, both pre- and postnatal, can lead to neuroendocrine perturbations, including hypothalamic-pituitary-adrenal axis dysregulation and inflammation persisting up to adulthood. This process, commonly referred to… read more here.
Keywords: adversity long; life adversity; early life; neurobehavioral outcomes ... See more keywords