Maternal Socs3 knockdown attenuates postnatal obesity caused by an early life environment of maternal obesity and intrauterine overnutrition in progeny mice
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DOI: 10.1002/iub.2526
Abstract: Pathological states in the early life environment of mammalian offspring, including maternal obesity and intrauterine overnutrition, can induce obesity and metabolic disorder later in life. Leptin resistance caused by upregulation of Socs3 in the hypothalamus… read more here.
Keywords: life environment; socs3; group; early life ... See more keywords
Sex and gender differences in developmental programming of metabolism
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DOI: 10.1016/j.molmet.2018.04.007
Abstract: Background The early life environment experienced by an individual in utero and during the neonatal period is a major factor in shaping later life disease risk-including susceptibility to develop obesity, diabetes, and cardiovascular disease. The… read more here.
Keywords: life environment; early life; disease; sex ... See more keywords
The early-life environment of a pig shapes the phenotypes of its social partners in adulthood
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DOI: 10.1038/hdy.2017.3
Abstract: Social interactions among individuals are abundant, both in natural and domestic populations, and may affect phenotypes of individuals. Recent research has demonstrated that the social effect of an individual on the phenotype of its social… read more here.
Keywords: life environment; phenotypes social; social partners; early life ... See more keywords
Rehabilitation in the real-life environment of a shopping mall
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DOI: 10.1080/09638288.2016.1277394
Abstract: Abstract Aim: The aim of this study was to explore how shopping malls could be used during rehabilitation and to identify the facilitators and barriers to their use. Method: Two focus groups, conducted with 15… read more here.
Keywords: life environment; mall; rehabilitation; real life ... See more keywords
Early-life environment and differences in costs of reproduction in a preindustrial human population
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DOI: 10.1371/journal.pone.0207236
Abstract: Reproduction is predicted to trade-off with long-term maternal survival, but the survival costs often vary between individuals, cohorts and populations, limiting our understanding of this trade-off, which is central to life-history theory. One potential factor… read more here.
Keywords: life environment; reproduction; early life; trade ... See more keywords
Adverse Early Life Environment Restricts Growth and Increases Hepatic Lipid Content
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DOI: 10.1542/peds.142.1_meetingabstract.253
Abstract: Background: Children exposed to adverse early life environment (AELE) carry increased risk of growth restriction and metabolic disease, including non-alcoholic fatty liver disease (NAFLD). NAFLD occurs in animal models of maternal Western diet. Animal models… read more here.
Keywords: life environment; growth; adverse early; early life ... See more keywords