Preclinical safety and efficacy of cannabidivarin for early life seizures
Sign Up to like & getrecommendations! Published in 2019 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2019.01.002
Abstract: ABSTRACT A significant proportion of neonatal and childhood seizures are poorly controlled by existing anti‐seizure drugs (ASDs), likely due to prominent differences in ionic homeostasis and network connectivity between the immature and mature brain. In… read more here.
Keywords: safety; early life; cbdv; efficacy ... See more keywords
The Effect of Early-Life Seizures on Cognitive and Motor Development: A Case Series
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric Physical Therapy"
DOI: 10.1097/pep.0000000000000918
Abstract: Purpose: This case series documents developmental changes over time and in response to a novel intervention, Sitting Together and Reaching to Play (START-Play), in children with early-life seizures. Methods: Thirteen children with early-life seizures were… read more here.
Keywords: early life; development; life seizures; motor ... See more keywords
Multiple Early-Life Seizures Alters Neonatal Communicative Behavior in Fmr1 Knockout Mice
Sign Up to like & getrecommendations! Published in 2022 at "Developmental Neuroscience"
DOI: 10.1159/000524898
Abstract: Fragile X syndrome (FXS) is the leading monogenic cause of intellectual disability and a significant contributor to Autism Spectrum Disorder. Individuals with FXS are subject to developing numerous comorbidities, one of the most prevalent being… read more here.
Keywords: early life; life seizures; knockout mice; fmr1 knockout ... See more keywords