O-GlcNAcylation of SKN-1 modulates the lifespan and oxidative stress resistance in Caenorhabditis elegans
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DOI: 10.1038/srep43601
Abstract: In C. elegans, the transcription factor skinhead-1 (SKN-1), the ortholog of human NF-E2-related factor 2 (Nrf-2), plays important roles in oxidative stress defense and aging processes. It has been documented that the activity of SKN-1… read more here.
Keywords: skn; stress resistance; lifespan oxidative; oxidative stress ... See more keywords