Increased Akt signaling in the fat body of Anopheles stephensi extends lifespan and increases lifetime fecundity through modulation of insulin-like peptides.
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DOI: 10.1016/j.jinsphys.2019.103932
Abstract: Insulin-like peptides (ILPs) and the insulin/insulin-like growth factor 1 signaling (IIS) cascade regulate numerous physiological functions, including lifespan, reproduction, immunity, and metabolism, in diverse eukaryotes. We previously demonstrated that in female Anopheles stephensi and Aedes… read more here.
Keywords: fat body; lifetime fecundity; insulin like; like peptides ... See more keywords