Polymorphisms of DNA repair genes XRCC1 and LIG4 and idiopathic male infertility
Sign Up to like & getrecommendations! Published in 2017 at "Systems Biology in Reproductive Medicine"
DOI: 10.1080/19396368.2017.1374488
Abstract: ABSTRACT Sperm DNA damage is one of the associated factors of idiopathic male infertility and abnormal spermatogenesis. This study was conducted to assess possible association between risk of male infertility with X-ray repair cross complementing… read more here.
Keywords: risk; lig4; male infertility; infertility ... See more keywords
Lig3-dependent rescue of mouse viability and DNA double-strand break repair by catalytically inactive Lig4
Sign Up to like & getrecommendations! Published in 2024 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkae1216
Abstract: Abstract Recent studies have revealed a structural role for DNA ligase 4 (Lig4) in the maintenance of a repair complex during non-homologous end joining (NHEJ) of DNA double-strand breaks. In cultured cell lines, catalytically inactive… read more here.
Keywords: inactive lig4; lig4; repair; catalytically inactive ... See more keywords