CTHRC1 Knockdown Promotes Inflammatory Responses Partially by p38 MAPK Activation in Human Periodontal Ligament Cells.
Sign Up to like & getrecommendations! Published in 2021 at "Inflammation"
DOI: 10.1007/s10753-021-01461-8
Abstract: Collagen triple helix repeat containing 1 (CTHRC1), a secreted glycoprotein, is widely expressed in many tissues. It has been recently defined as a novel marker for rheumatoid arthritis (RA), a systemic inflammatory disorder. However, the… read more here.
Keywords: p38 mapk; periodontal ligament; cthrc1 knockdown; cthrc1 ... See more keywords
Development of in situ gel containing asiaticoside/cyclodextrin complexes. Evaluation in culture human periodontal ligament cells (HPLDCs).
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.119589
Abstract: Asiaticoside (AS), an active herbal compound isolated from Centella asiatica, has the potential benefit in promoting type I collagen (COL I) synthesis and osteogenic differentiation in human periodontal ligament cells (HPDLCs). However, it has low… read more here.
Keywords: periodontal ligament; ligament cells; situ; human periodontal ... See more keywords
Effect of propolis on preserving human periodontal ligament cells and regulating pro‐inflammatory cytokines
Sign Up to like & getrecommendations! Published in 2018 at "Dental Traumatology"
DOI: 10.1111/edt.12411
Abstract: BACKGROUND/AIM Propolis has been suggested as a storage medium for avulsed teeth. The aim of this study was to compare the effectiveness of Brazilian propolis with Hank's balanced salt solution and milk in maintaining the… read more here.
Keywords: periodontal ligament; human periodontal; propolis; ligament cells ... See more keywords
Human periodontal ligament cells exhibit no endotoxin tolerance upon stimulation with Porphyromonas gingivalis lipopolysaccharide
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Periodontal Research"
DOI: 10.1111/jre.12549
Abstract: Background/Objectives Endotoxin tolerance is characterized by a state of hyporesponsiveness after confrontation with endotoxins such as lipopolysaccharides (LPS) at low concentrations. The aim of this study was to investigate, whether pretreatment with Porphyromonas gingivalis leads… read more here.
Keywords: periodontal ligament; tolerance; porphyromonas gingivalis; ligament cells ... See more keywords
Effect of lentivirus-mediated BMP2 from autologous tooth on the proliferative and osteogenic capacity of human periodontal ligament cells.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of periodontal research"
DOI: 10.1111/jre.13025
Abstract: BACKGROUND AND OBJECTIVE Periodontitis is a chronic progressive inflammation that invades periodontal supporting tissues, in which periodontal tissue regeneration engineering offers new hope for prevention and treatment, including seed cells, scaffolds, and growth factors. In… read more here.
Keywords: human periodontal; effect; bmp2; ligament cells ... See more keywords
MicroRNA-203 mediates P. gingivalis LPS-induced inflammation and differentiation of periodontal ligament cells.
Sign Up to like & getrecommendations! Published in 2022 at "Oral diseases"
DOI: 10.1111/odi.14132
Abstract: AIM In this study, we aimed to explore the effects of microRNA-203 (miR-203) on P. gingivalis lipopolysaccharide (P.g. LPS)-stimulated periodontal ligament cells (PDLCs) and identify potential molecular targets for periodontitis treatment. METHODS PDLCs were stimulated… read more here.
Keywords: mir 203; ligament cells; lps induced; differentiation ... See more keywords
Effects of Ginsenoside Rg1 on the Biological Activity of Human Periodontal Ligament Cells
Sign Up to like & getrecommendations! Published in 2022 at "BioMed Research International"
DOI: 10.1155/2022/7576359
Abstract: , Objective. To investigate the effect of ginsenoside Rg1 on the biological activity of primary cultured human periodontal ligament cells (PDLC). Methods. The effects of ginsenoside Rg1 on the proliferation activity, protein synthesis, and alkaline… read more here.
Keywords: activity; ligament cells; ginsenoside rg1; periodontal ligament ... See more keywords
Cyclic compression emerged dual effects on the osteogenic and osteoclastic status of LPS-induced inflammatory human periodontal ligament cells according to loading force
Sign Up to like & getrecommendations! Published in 2020 at "BMC Oral Health"
DOI: 10.1186/s12903-019-0987-y
Abstract: BackgroundAppropriate mechanical stimulation is essential for bone homeostasis in healthy periodontal tissues. While the osteogenesis and osteoclast differentiation of inflammatory periodontal ligament cells under different dynamic loading has not been yet clear. The aim of… read more here.
Keywords: periodontal ligament; ligament cells; stress; inflammatory human ... See more keywords
Exosomes from Tension Force-Applied Periodontal Ligament Cells Promote Mesenchymal Stem Cell Recruitment by Altering microRNA Profiles
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Stem Cells"
DOI: 10.15283/ijsc21170
Abstract: Background and Objectives To investigate the role of exosomes from periodontal ligament cells (PDLCs) in bone marrow mesenchymal stem cell (BMSC) migration. Methods and Results Human PDLCs were applied cyclic tension stretching. Exosomes were extracted… read more here.
Keywords: stem cell; ligament cells; mesenchymal stem; mir ... See more keywords
Age Related Senescence, Apoptosis, and Inflammation Profiles in Periodontal Ligament Cells from Canine Teeth.
Sign Up to like & getrecommendations! Published in 2022 at "Current molecular medicine"
DOI: 10.2174/1566524022666220520124630
Abstract: OBJECTIVE The periapical tissues including periodontal ligament cells (PDLCs) are playing an important role in repairing the surrounding tissue of the teeth. A decrease in the regenerative potentiality of resident stem cells (PDLCs) has been… read more here.
Keywords: inflammation; apoptosis; ligament cells; expression ... See more keywords
Exosomes from Cyclic Stretched Periodontal Ligament Cells Induced Periodontal Inflammation through miR-9-5p/SIRT1/NF-κB Signaling Pathway.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of immunology"
DOI: 10.4049/jimmunol.2300074
Abstract: Abundant evidence demonstrates that mechanical stress could induce an inflammatory response in periodontal tissue, but the precise mechanism remains unclear. In the past few years, periodontal ligament cells (PDLCs), as the most force-sensitive cells, have… read more here.
Keywords: signaling pathway; ligament cells; periodontal inflammation; mir ... See more keywords