TAZ promotes the proliferation and osteogenic differentiation of human periodontal ligament stem cells via the p‐SMAD3
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29346
Abstract: This study aims to offer insights about the biological influence of TAZ, which is a transcriptional coactivator containing a PDZ‐binding motif, upon the apoptosis, proliferation, and osteogenic differentiation of human periodontal ligament stem cells (h‐PDLSCs). read more here.
Keywords: periodontal ligament; differentiation human; proliferation osteogenic; osteogenic differentiation ... See more keywords
Periodontal ligament stem cells in the periodontitis niche: inseparable interactions and mechanisms
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.4mr0421-750r
Abstract: Periodontitis is characterized by the periodontium's pathologic destruction due to the host's overwhelmed inflammation to the dental plaque. The bacterial infections and subsequent host immune responses have shaped a distinct microenvironment, which generally affects resident… read more here.
Keywords: periodontal ligament; stem cells; ligament stem; niche ... See more keywords
Periodontal Ligament Stem Cells: Current Knowledge and Future Perspectives.
Sign Up to like & getrecommendations! Published in 2019 at "Stem cells and development"
DOI: 10.1089/scd.2019.0025
Abstract: Teeth represent a fascinating area of study in regenerative medicine, because of their unique and complex developmental origin. Several types of mesenchymal stem cells (MSCs) have been characterized in the oral cavity, and those derived… read more here.
Keywords: periodontal ligament; pdl; stem; ligament stem ... See more keywords
The long non-coding RNA landscape of periodontal ligament stem cells subjected to compressive force.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of orthodontics"
DOI: 10.1093/ejo/cjy057
Abstract: Objective The role of long non-coding ribonucleic acids (lncRNAs) during orthodontic tooth movement remains unclear. We explored the lncRNA landscape of periodontal ligament stem cells (PDLSCs) subjected to compressive force. Materials and methods PDLSCs were… read more here.
Keywords: periodontal ligament; landscape periodontal; long non; non coding ... See more keywords
Mechanical force modulates periodontal ligament stem cell characteristics during bone remodelling via TRPV4
Sign Up to like & getrecommendations! Published in 2020 at "Cell Proliferation"
DOI: 10.1111/cpr.12912
Abstract: Mechanical force plays an important role in modulating stem cell fate and behaviours. However, how periodontal ligament stem cells (PDLSCs) perceive mechanical stimulus and transfer it into biological signals, and thereby promote alveolar bone remodelling,… read more here.
Keywords: periodontal ligament; stem cell; mechanical force; stem ... See more keywords
Mechanobiology of Periodontal Ligament Stem Cells in Orthodontic Tooth Movement
Sign Up to like & getrecommendations! Published in 2018 at "Stem Cells International"
DOI: 10.1155/2018/6531216
Abstract: Periodontal ligament stem cells (PDLSCs) possess self-renewal, multilineage differentiation, and immunomodulatory properties. They play a crucial role in maintaining periodontal homeostasis and also participated in orthodontic tooth movement (OTM). Various studies have applied controlled mechanical… read more here.
Keywords: periodontal ligament; tooth movement; stem; ligament stem ... See more keywords
Mechanical Stress Modulates the RANKL/OPG System of Periodontal Ligament Stem Cells via α7 nAChR in Human Deciduous Teeth: An In Vitro Study
Sign Up to like & getrecommendations! Published in 2019 at "Stem Cells International"
DOI: 10.1155/2019/5326341
Abstract: The aim of this study was to investigate the mechanism by which periodontal ligament stem cells (PDLSCs) modulate root resorption of human deciduous teeth under mechanical stress. In this investigation, the PDLSCs were derived from… read more here.
Keywords: periodontal ligament; mechanical stress; ligament stem; stem cells ... See more keywords
Translating proteome and transcriptome dynamics of periodontal ligament stem cell-derived secretome/conditioned medium in an in vitro model of periodontitis
Sign Up to like & getrecommendations! Published in 2024 at "BMC Oral Health"
DOI: 10.1186/s12903-024-04167-z
Abstract: Periodontal ligament stem cells (PDLSCs) have been proposed as therapeutic candidates in periodontal diseases and periodontium defects. Paracrine factors of PDLSCs, namely, secretome, can contribute to tissue regeneration comparable to direct stem cell application. This… read more here.
Keywords: stem cell; stem; ligament stem; pdlsc ... See more keywords
Lapine periodontal ligament stem cells for musculoskeletal research in preclinical animal trials
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Translational Medicine"
DOI: 10.1186/s12967-018-1551-2
Abstract: BackgroundHuman periodontal ligament stem cells (hPDLSCs) have been shown to be a reliable source of mesenchymal stem cells (MSCs). On the other hand, rabbits have been commonly used in preclinical trials for musculoskeletal research. However,… read more here.
Keywords: hpdl cells; periodontal ligament; rpdl cells; ligament stem ... See more keywords
Long Non-coding RNA FER1L4 Mediates the Autophagy of Periodontal Ligament Stem Cells Under Orthodontic Compressive Force via AKT/FOXO3 Pathway
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.631181
Abstract: Orthodontic tooth movement is achieved by periodontal tissue remodeling triggered by mechanical force. It is essential to investigate the reaction of periodontal ligament stem cells (PDLSCs) for improving orthodontic therapeutic approaches. Autophagy is an endogenous… read more here.
Keywords: periodontal ligament; compressive force; fer1l4; force ... See more keywords
Maresin-1 and Resolvin E1 Promote Regenerative Properties of Periodontal Ligament Stem Cells Under Inflammatory Conditions
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.585530
Abstract: Maresin-1 (MaR1) and Resolvin E1 (RvE1) are specialized pro-resolving lipid mediators (SPMs) that regulate inflammatory processes. We have previously demonstrated the hard and soft tissue regenerative capacity of RvE1 in an in vivo model of… read more here.
Keywords: periodontal ligament; regenerative properties; rve1; ligament stem ... See more keywords