Ligand- and Additive-Free 2-Position-Selective Trifluoromethylation of Heteroarenes Under Ambient Conditions
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DOI: 10.3389/fchem.2019.00613
Abstract: A highly selective copper-catalyzed trifluoromethylation of indoles is reported with the assistance of a removable directing group. This protocol provides an easy and rapid method to various 2-position-selective trifluoromethylated heteroarenes including indoles, pyrroles, benzofuran, and… read more here.
Keywords: additive free; trifluoromethylation; ambient conditions; position selective ... See more keywords