Metal‐Ligand Complexes as Multifunctional Platforms for Photo‐Activated Cancer Therapy
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202504575
Abstract: Metal‐ligand complexes have emerged as versatile platforms for photo‐activated therapy (PAT) for cancer, including photothermal therapy, photodynamic therapy, and photo‐activated chemotherapy. This review explores the unique optical properties and tunable characteristics of these complexes, which… read more here.
Keywords: cancer; ligand complexes; therapy; ligand ... See more keywords
Exploration of Novel Nickel(II) and Copper(II)–Levofloxacin Mixed‐Ligand Complexes: Structural Study, DFT Insights, Molecular Docking, and In Vitro Bioactivity Assessment
Sign Up to like & getrecommendations! Published in 2025 at "Applied Organometallic Chemistry"
DOI: 10.1002/aoc.70108
Abstract: In this study, we combined NiCl2 and CuCl2 with levofloxacin (LEV) in the presence of 2,6‐di(1H‐pyrazol‐1‐yl)pyridine (DPP) to generate two novel NiLEVDPP and CuLEVDPP mixed‐ligand complexes. Evaluating their antibacterial, antifungal, anti‐inflammatory, and antioxidant properties was… read more here.
Keywords: molecular docking; spectroscopy; ligand complexes; levofloxacin ... See more keywords
Spectroscopic, Structural Analysis, Molecular Orbital, Molecular Docking, and Antibacterial Activity of the Thiocarbohydrazone Ligand and Its Complexes
Sign Up to like & getrecommendations! Published in 2025 at "Applied Organometallic Chemistry"
DOI: 10.1002/aoc.7956
Abstract: New thiocarbohydrazone ligand (N′‐((E)‐3,3‐diphenyl‐2,3‐dihydro‐1H‐inden‐1‐ylidene)‐2‐((Z)‐2‐oxoindolin‐3‐ylidene)hydrazine‐1‐carbothiohydrazide; H2L) and its Co (II), Ni (II), Fe (III), Cu (II), Cd (II), Zn (II), and Mn (II) complexes were prepared in good yields ranging from 60% to 90% and characterized… read more here.
Keywords: molecular docking; spectroscopic structural; ligand complexes; ligand ... See more keywords
Receptor pharmacophore ensemble (REPHARMBLE): a probabilistic pharmacophore modeling approach using multiple protein-ligand complexes
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Modeling"
DOI: 10.1007/s00894-018-3820-7
Abstract: Ensemble methods are gaining more importance in structure-based approaches as single protein-ligand complexes strongly influence the outcomes of virtual screening. Structure-based pharmacophore modeling based on a single protein-ligand complex with complex feature combinations is often… read more here.
Keywords: ligand complexes; pharmacophore ensemble; ligand; protein ligand ... See more keywords
New biologically active mixed-ligand Co(II) and Ni(II) complexes of enrofloxacin
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Thermal Analysis and Calorimetry"
DOI: 10.1007/s10973-018-6994-4
Abstract: New mixed-ligand Co(II) and Ni(II) complexes with enrofloxacin and 1,10-phenanthroline/8-hydroxyquinoline have been synthesized. The metal complexes have been characterized by elemental analyses, molar conductance, FT-IR, solid reflectance, magnetic moment, thermal analyses, X-ray powder diffraction (XRD)… read more here.
Keywords: ligand complexes; complexes enrofloxacin; metal complexes; mixed ligand ... See more keywords
Synthesis, structural elucidation, in vitro antibacterial activity, DFT calculations, and molecular docking aspects of mixed-ligand complexes of a novel oxime and phenylalanine.
Sign Up to like & getrecommendations! Published in 2022 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2022.105685
Abstract: An oxime ligand (HL) was synthesized by the condensation of 4-biphenylhydroxymoyl chloride with 2-amino-5-bromopyridine. The oxime ligand was reacted with l-phenylalanine and metal(II) acetate salts (Co(II), Ni(II), and Cu(II)) to synthesize mixed-ligand complexes. Structural elucidation… read more here.
Keywords: ligand complexes; molecular docking; ligand; structural elucidation ... See more keywords
Synthesis, characterization of Uranyl(VI), Th(IV), Zr(IV) mixed-ligand complexes with S-methyl-2-(4-methoxybenzylidine)dithiocarbazate and N-donor co-ligand, and their evaluation as antimicrobial agent
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Saudi Chemical Society"
DOI: 10.1016/j.jscs.2021.101207
Abstract: Abstract Schiff base, S-methyl-2-(4-methoxybenzylidine) dithiocarbazate as a primary ligand (HL1), quinoline (L2) as a co-ligand, and hydrated metal salts have been reacted in ethanol in 1:2:1 molar ratio to produce mixed-ligand complexes of the type,… read more here.
Keywords: methoxybenzylidine dithiocarbazate; methyl methoxybenzylidine; ligand complexes; mixed ligand ... See more keywords
Structural characterization and biological activity of a new metal complexes based of Schiff base
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2021.115522
Abstract: Abstract Metal complexes of Co(II), Ni(II) and Cu(II) complexes (1–3) with a new Schiff base (HL) have been prepared and characterized by elemental analyses IR, UV–Visible, magnetic measurements, 1H NMR, 13C NMR, and X-ray diffraction… read more here.
Keywords: structural characterization; ligand complexes; metal complexes; activity ... See more keywords
Synthesis, structure characterization and biological activity of selected metal complexes of sulfonamide Schiff base as a primary ligand and some mixed ligand complexes with glycine as a secondary ligand
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2016.12.070
Abstract: Abstract The current work reports synthesis of metal complexes and mixed ligand complexes of a novel sulfonamide Schiff base ligand (HL) resulted from the condensation of sulfametrole [ N ′ -(4-methoxy-1,2,5-thiadiazol-3-yl]sulfanilamide and acetyl-acetone as a… read more here.
Keywords: ligand complexes; metal complexes; mixed ligand; ligand ... See more keywords
Synthesis, characterization, anticancer properties and theoretical study of asymmetrical Cd(II) N2-Schiff base complexes
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2018.08.072
Abstract: Abstract In this study, synthesis, characterization and anticancer properties of four cadmium(II) complexes of a new asymmetrical bidentate Schiff base ligand (abbreviated as L) with a CdLX2 (X = Cl−, Br−, I− and SCN−) general formula are… read more here.
Keywords: synthesis characterization; ligand complexes; characterization anticancer; ligand ... See more keywords
Synthesis, characterization, molecular modeling and preliminary biochemical evaluation of new copper (II) mixed-ligand complexes
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2020.129695
Abstract: Abstract Three new Cu(II) mixed-ligand complexes of the type [Cu(primary ligand)(secondary co-ligand)], were synthesized, characterized and preliminary tested for their biochemical activities. The primary ligand (HL) was derived from condensation of p-toluidine with 2-hydroxy-naphthalhyde. Three… read more here.
Keywords: ligand complexes; molecular modeling; mixed ligand; ligand ... See more keywords