Effective Ligand Design: Zinc Complexes with Guanidine Hydroquinoline Ligands for Fast Lactide Polymerization and Chemical Recycling.
Sign Up to like & getrecommendations! Published in 2022 at "ChemSusChem"
DOI: 10.1002/cssc.202201603
Abstract: Invited for this month's cover is the group of Sonja Herres-Pawlis at RWTH Aachen University. The image shows how the zinc guanidine complexes help a circular economy of bioplastics by mediating the ring-opening polymerization of… read more here.
Keywords: design zinc; zinc complexes; complexes guanidine; effective ligand ... See more keywords
Ligand Design for Modulation of RXR Functions.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9585-1_4
Abstract: Retinoid X receptors (RXRs) are promiscuous partners of heterodimeric associations with other members of the Nuclear Receptor (NR) superfamily. RXR ligands ("rexinoids") either transcriptionally activate the "permissive" subclass of heterodimers or synergize with partner ligands… read more here.
Keywords: modulation rxr; ligand design; rxr functions; design modulation ... See more keywords
Switching the Spin-Crossover Phenomenon by Ligand Design on Imidazole-Diazineiron(II) Complexes.
Sign Up to like & getrecommendations! Published in 2018 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.8b02278
Abstract: The iron(II) complexes of two structural isomers of 2-(1 H-imidazol-2-yl)diazine reveal how ligand design can be a successful strategy to control the electronic and magnetic properties of complexes by fine-tuning their ligand field. The two… read more here.
Keywords: ligand design; spin crossover; spin;
Ligand design of zero-field splitting in trigonal prismatic Ni(II) cage complexes.
Sign Up to like & getrecommendations! Published in 2022 at "Dalton transactions"
DOI: 10.1039/d1dt02156g
Abstract: Complexes of encapsulated metal ions are promising potential metal-based electron paramagnetic resonance imaging (EPRI) agents due to zero-field splitting. Herein, we synthesize and magnetically characterize a series of five new Ni(II) complexes based on a… read more here.
Keywords: zero field; design zero; ligand design; field splitting ... See more keywords
A ligand design strategy to enhance catalyst stability for efficient formic acid dehydrogenation.
Sign Up to like & getrecommendations! Published in 2023 at "Dalton transactions"
DOI: 10.1039/d2dt04079d
Abstract: New Ir complexes bearing N-(methylsulfonyl)-2-pyridinecarboxamide (C1) and N-(phenylsulfonyl)-2-pyridinecarboxamide (C2) were employed as catalysts for aqueous formic acid dehydrogenation (FADH). The ligands were designed to maintain the picolinamide skeleton and introduce strong sigma sulfonamide moieties. C1… read more here.
Keywords: stability; formic acid; acid dehydrogenation; ligand design ... See more keywords
Placing gold on a π+-surface: ligand design and impact on reactivity
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc05574k
Abstract: We describe a novel gold chloride complex supported by an ambiphilic phosphine/xanthylium ligand in which the AuCl moiety interacts with the π+ surface of the xanthylium unit as indicated by structural studies. Energy decomposition analyses… read more here.
Keywords: placing gold; surface ligand; design impact; ligand ... See more keywords
The Neurokinins: Peptidomimetic Ligand Design and Therapeutic Applications.
Sign Up to like & getrecommendations! Published in 2018 at "Current medicinal chemistry"
DOI: 10.2174/0929867325666180913095918
Abstract: The neurokinins are indisputably essential neurotransmitters in numerous patho- and physiological events. Being widely distributed in the central nervous system (CNS) and peripheral tissues, their discovery rapidly promoted them to drugs targets. A necessity for… read more here.
Keywords: ligand design; non peptidic; peptidomimetic ligand; neurokinins peptidomimetic ... See more keywords
Class A GPCRs: Structure, Function, Modeling and Structure-based Ligand Design.
Sign Up to like & getrecommendations! Published in 2017 at "Current pharmaceutical design"
DOI: 10.2174/1381612823666170710151255
Abstract: G protein-coupled receptors (GPCRs), especially the class A, are the most heavily investigated drug targets in the pharmaceutical industry. Tremendous efforts have been made by both industry and academia to understand the molecular structure and… read more here.
Keywords: ligand design; class; structure; structure function ... See more keywords
Ligand design for riboswitches, an emerging target class for novel antibiotics.
Sign Up to like & getrecommendations! Published in 2017 at "Future medicinal chemistry"
DOI: 10.4155/fmc-2017-0063
Abstract: Riboswitches are cis-acting gene regulatory elements and constitute potential targets for new antibiotics. Recent studies in this field have started to explore these targets for drug discovery. New ligands found by fragment screening, design of… read more here.
Keywords: ligand design; design riboswitches; design; emerging target ... See more keywords