Articles with "ligand expression" as a keyword



Clinical performance of endobronchial ultrasound‐guided transbronchial needle aspiration for assessing programmed death ligand‐1 expression in nonsmall cell lung cancer

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Published in 2018 at "Diagnostic Cytopathology"

DOI: 10.1002/dc.23900

Abstract: Pembrolizumab was recently approved as a first line agent for metastatic NSCLC in patients with high programmed death‐ligand 1 (PD‐L1) expression. read more here.

Keywords: ligand expression; programmed death; death ligand;

NKG2D ligand expression on NK cells induces NKG2D-mediated cross-tolerization of cytokine signaling and reduces NK cell tumor immunity.

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Published in 2025 at "Journal of immunology"

DOI: 10.1093/jimmun/vkaf030

Abstract: Studies support a role for natural killer (NK) cells in cancer control, making these cells attractive for immunotherapy. One method being tested to make effective NK cells is the ex vivo activation with interleukin (IL)-12,… read more here.

Keywords: ligand expression; induces nkg2d; nkg2d ligand; tumor ... See more keywords

Programmed death ligand-1 expression and occult lymph node metastasis in non-small cell lung cancer.

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Published in 2023 at "Thoracic cancer"

DOI: 10.1111/1759-7714.14922

Abstract: BACKGROUND Identifying the preoperative risk factors for lymph node upstaging could contribute to the development of individualized perioperative treatment for patients with non-small cell lung cancer (NSCLC). The current study aimed to evaluate the risk… read more here.

Keywords: programmed death; ligand expression; death ligand;

Epidermal programmed cell death‐ligand 1 expression in TEN associated with nivolumab therapy

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Published in 2017 at "Journal of Cutaneous Pathology"

DOI: 10.1111/cup.12876

Abstract: Nivolumab is a programmed cell death receptor‐1 (PD‐1) antibody used in the treatment of metastatic or unresectable melanoma. Cutaneous reactions are the most common adverse events reported with these agents and are rarely severe or… read more here.

Keywords: death; ligand expression; death ligand; programmed cell ... See more keywords

Regulation of Synovial γδ T Cell Ligand Expression by Mitochondrial Reactive Oxygen Species and Gasdermin-D.

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Published in 2022 at "Journal of immunology"

DOI: 10.4049/jimmunol.2101166

Abstract: γδ T cells reside at mucosal and epithelial barriers, and they often accumulate at sites of inflammation, both infectious and autoimmune, as well as in certain tumors. However, progress in understanding their function is considerably… read more here.

Keywords: synovial cell; mitochondrial reactive; ligand expression; expression ... See more keywords