Multi-ligand functionalized blood-to-tumor sequential targeting strategies in the field of glioblastoma nanomedicine.
Sign Up to like & getrecommendations! Published in 2023 at "Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology"
DOI: 10.1002/wnan.1893
Abstract: Glioblastoma (GBM) is an unmet clinical need characterized by a standard of care (SOC) 5-year survival rate of only 5%, and a treatment mostly palliative. Significant hurdles in GBM therapies include an effective penetration of… read more here.
Keywords: ligand functionalized; multi ligand; brain; tumor ... See more keywords
Synthesis of urea-pyridyl ligand functionalized mesoporous silica hybrid material for hydrophobic and hydrophilic drug delivery application
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Porous Materials"
DOI: 10.1007/s10934-017-0425-y
Abstract: In this work, we propose the synthesis of urea-pyridyl (UPy) ligand functionalized mesoporous silica hybrid material as novel and effective drug delivery system for loading/release of both hydrophobic and hydrophilic drugs. For the synthesis of… read more here.
Keywords: ligand functionalized; mesoporous silica; drug; functionalized mesoporous ... See more keywords
Specific Binding of Ligand-Functionalized Thermoresponsive Microgels: Effect of Architecture, Ligand Density, and Hydrophobicity.
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c00725
Abstract: The biomolecular interaction of ligand-presenting switchable microgels is studied with respect to the polymer type, composition, and structure of the microgels. Monodisperse microgels are prepared through precipitation polymerization of N-isopropylacrylamide (PNIPAM microgels) or oligo(ethylene glycol… read more here.
Keywords: specific binding; density; ligand functionalized; ligand density ... See more keywords
Antifungal Encapsulated into Ligand-Functionalized Nanoparticles with High Specificity for Macrophages
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14091932
Abstract: Infectious diseases caused by intracellular microorganisms such as Histoplasma capsulatum represent a significant challenge worldwide. Drug encapsulation into functionalized nanoparticles (NPs) is a valuable alternative to improving drug solubility and bioavailability, preventing undesirable interactions and… read more here.
Keywords: ligand functionalized; antifungal encapsulated; encapsulated ligand; functionalized nanoparticles ... See more keywords