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Published in 2018 at "Bone"
DOI: 10.1016/j.bone.2018.01.002
Abstract: The large majority of cases of the autosomal dominant human disease fibrodysplasia ossificans progressiva (FOP) are caused by gain-of-function Arg206His mutations in the BMP type I receptor ACVR1 (ALK2). The Arg206His mutation is located in…
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Keywords:
acvr1 gly328;
bmp;
ligand independent;
bmp ligand ... See more keywords
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Published in 2022 at "Cell reports"
DOI: 10.1016/j.celrep.2022.110583
Abstract: In mature B cells, TACI controls class-switch recombination and differentiation into plasma cells during T cell-independent antibody responses. TACI binds the ligands BAFF and APRIL. Approximately 10% of patients with common variable immunodeficiency (CVID) carry TACI…
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Keywords:
activated cells;
ligand independent;
taci;
transmembrane domain ... See more keywords
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Published in 2022 at "Cancer Science"
DOI: 10.1111/cas.15653
Abstract: Chemoresistance is the crux of clinical treatment failure of small‐cell lung cancer (SCLC). Cancer stem cells play a critical role in therapeutic resistance of malignant tumors. Studies have shown that the role of erythropoietin‐producing hepatocellular…
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Keywords:
ligand independent;
small cell;
prmt1;
epha2 ... See more keywords