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   Articles with "ligand induced" as a keyword



Ligand‐Induced Crystallization Control in MAPbBr3 Hybrid Perovskites for High Quality Nanostructured Films

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recommendations! Published in 2025 at "Advanced Optical Materials"

DOI: 10.1002/adom.202402441

Abstract: Controlling the formation of hybrid perovskite thin films is crucial in obtaining high‐performance optoelectronic devices, since factors like morphology and film thickness have a profound impact on a film's functionality. For light‐emitting applications grain sizes… read more here.

Keywords: ligand induced; crystallization; crystallization control; mapbbr3 hybrid ... See more keywords

Investigating Protein Binding with the Isothermal Ligand‐induced Resolubilization Assay

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recommendations! Published in 2024 at "ChemBioChem"

DOI: 10.1002/cbic.202300773

Abstract: Target engagement assays typically detect and quantify the direct physical interaction of a protein of interest and its ligand through stability changes upon ligand binding. Commonly used target engagement methods detect ligand‐induced stability by subjecting… read more here.

Keywords: ligand induced; ligand; protein; isothermal ligand ... See more keywords

Au15Ag3(SPhMe2)14 Nanoclusters – Crystal Structure and Insights into Ligand-Induced Variation

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recommendations! Published in 2017 at "European Journal of Inorganic Chemistry"

DOI: 10.1002/ejic.201601513

Abstract: Understanding the ligand effects in the nanocluster (NC) range is crucial for tailoring the properties. We herein report on the crystal structure of the Au15Ag3(SPhMe2)14 nanocluster. Compared with the previously reported Au15Au3(SC6H11)14 nanocluster, Au15Ag3(SPhMe2)14 exhibits… read more here.

Keywords: crystal structure; au15ag3 sphme2; ligand induced; induced variation ... See more keywords

Direct comparison of the structural dynamics between spontaneous and ligand‐induced folding of staphylococcal nuclease

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recommendations! Published in 2025 at "Protein Science"

DOI: 10.1002/pro.70135

Abstract: Despite numerous studies focusing on the folding mechanism of globular proteins as well as ligand‐induced folding of intrinsically disordered proteins (IDPs), a unified framework for understanding both types of folding mechanisms has remained elusive. To… read more here.

Keywords: ligand induced; induced folding; structural dynamics; staphylococcal nuclease ... See more keywords
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Ligand-induced structural transitions combined with paramagnetic ions facilitate unambiguous NMR assignments of methyl groups in large proteins.

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recommendations! Published in 2022 at "Journal of biomolecular NMR"

DOI: 10.1007/s10858-022-00394-0

Abstract: NMR spectroscopy allows the study of biomolecules in close-to-native conditions. Structural information can be inferred from the NMR spectra when an assignment is available. Protein assignment is usually a time-consuming task, being specially challenging in… read more here.

Keywords: methyl groups; induced structural; structural transitions; ligand induced ... See more keywords
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Ligand Induced Changes in the Assembly of Nicotinic Receptors

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recommendations! Published in 2017 at "Biophysical Journal"

DOI: 10.1016/j.bpj.2016.11.1626

Abstract: Tobacco smoking is the leading cause of preventable death in the world. Nicotine the primary compound found in tobacco smoke has been found to alter the assembly of some subtypes of nicotinic receptors. Although the… read more here.

Keywords: induced changes; assembly nicotinic; nicotinic receptors; ligand induced ... See more keywords

Ligand-induced glutathione transferase degradation as a therapeutic modality: Investigation of a new metal-mediated affinity cleavage strategy for human GSTP1-1.

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recommendations! Published in 2018 at "International journal of biological macromolecules"

DOI: 10.1016/j.ijbiomac.2018.04.187

Abstract: Glutathione transferases (GST, EC. 2.5.1.18) are overexpressed in cancer cell and have been shown to be involved in cancer cell growth, differentiation and the development of multi-drug resistance (MDR) mechanism. Therefore, GST inhibitors are emerging… read more here.

Keywords: degradation; cleavage; human gstp1; ligand induced ... See more keywords

Thermal shift assay: Strengths and weaknesses of the method to investigate the ligand-induced thermostabilization of soluble guanylyl cyclase.

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recommendations! Published in 2019 at "Journal of pharmaceutical and biomedical analysis"

DOI: 10.1016/j.jpba.2019.113065

Abstract: Thermal shift assay is a fluorescence dye based biochemical method to determine the melting point of a protein. It can be used to investigate the ligand-induced stabilization of proteins and helps to increase the likelihood… read more here.

Keywords: shift; shift assay; ligand induced; soluble guanylyl ... See more keywords
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Second-harmonic generation-based methods to detect and characterize ligand-induced RNA conformational changes.

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recommendations! Published in 2019 at "Methods"

DOI: 10.1016/j.ymeth.2019.05.012

Abstract: Second-harmonic generation (SHG) is a biophysical tool that senses ligand-induced conformational changes in biomolecules. The Biodesy Delta™ has been developed as a high-throughput screening platform to monitor conformational changes in proteins and oligonucleotides by SHG… read more here.

Keywords: harmonic generation; ligand induced; shg assay; conformational changes ... See more keywords

Ligand-Induced U Mobilization from Chemogenic Uraninite and Biogenic Noncrystalline U(IV) under Anoxic Conditions

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recommendations! Published in 2022 at "Environmental Science & Technology"

DOI: 10.1021/acs.est.1c07919

Abstract: Microbial reduction of soluble hexavalent uranium (U(VI)) to sparingly soluble tetravalent uranium (U(IV)) has been explored as an in situ strategy to immobilize U. Organic ligands might pose a potential hindrance to the success of… read more here.

Keywords: ligand induced; organic ligands; induced mobilization; noncrystalline ... See more keywords

Chemo-Selective Cys-Pen Disulfide for Proximity-Induced Cysteine Cross-Linking.

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recommendations! Published in 2022 at "ACS chemical biology"

DOI: 10.1021/acschembio.2c00083

Abstract: Disulfide-rich architectures are valuable pharmacological tools or therapeutics. Besides, a ligand-induced conjugate strategy offers potential advantages in potency, selectivity, and duration of action for novel covalent drugs. Combining the plentiful disulfide-rich architecture library and ligand-induced… read more here.

Keywords: ligand induced; disulfide; pen disulfide; cys pen ... See more keywords