The Nuclear Receptor PPAR&ggr; Controls Progressive Macrophage Polarization as a Ligand‐Insensitive Epigenomic Ratchet of Transcriptional Memory
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DOI: 10.1016/j.immuni.2018.09.005
Abstract: Graphical Abstract Figure. No caption available. SUMMARY Macrophages polarize into distinct phenotypes in response to complex environmental cues. We found that the nuclear receptor PPAR&ggr; drove robust phenotypic changes in macrophages upon repeated stimulation with… read more here.
Keywords: ligand insensitive; insensitive ppar; polarization; ppar ggr ... See more keywords