Ligand Pathways in Nuclear Receptors
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DOI: 10.1021/acs.jcim.9b00360
Abstract: Nuclear receptors (NRs) are ligand-inducible transcription factors that play an essential role in a multitude of physiological processes as well as diseases rendering them attractive drug targets. Crystal structures revealed the binding site of NRs… read more here.
Keywords: methodology; nuclear receptors; drug; pathways nuclear ... See more keywords
Ligand pathways in estrogen-related receptors
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DOI: 10.1080/07391102.2022.2027818
Abstract: Abstract The three subtypes of estrogen-related receptors ERRα, ERRβ, and ERRγ are nuclear receptors mediating metabolic processes in various tissues such as the skeletal muscle, fat tissue, bone, and liver. Although the knowledge on their… read more here.
Keywords: pathways estrogen; estrogen related; receptors ligand; ligand pathways ... See more keywords
Ligand pathways in neuroglobin revealed by low-temperature photodissociation and docking experiments
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DOI: 10.1107/s2052252519008157
Abstract: Ultralow-temperature X-ray crystallography, in crystallo microspectroscopy and X-ray absorption spectroscopy were used to study the carbon monoxide photodissociation intermediate in neuroglobin. Moreover, X-ray crystallography under high O2 pressure allowed the identification of a novel storage… read more here.
Keywords: pathways neuroglobin; ligand pathways; revealed low; temperature ... See more keywords