Ligand-Targeted Drug Delivery.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical reviews"
DOI: 10.1021/acs.chemrev.7b00013
Abstract: Safety and efficacy constitute the major criteria governing regulatory approval of any new drug. The best method to maximize safety and efficacy is to deliver a proven therapeutic agent with a targeting ligand that exhibits… read more here.
Keywords: ligand targeted; drug delivery; targeting ligand; drug ... See more keywords
Development of a Ligand-Targeted Therapeutic Agent for Neurokinin-1 Receptor Expressing Cancers.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.7b00583
Abstract: The neurokinin-1 receptor (NK1R) plays a significant role in the progression and metastasis of several neuroendocrine tumors. Due to its upregulation in these cancers, NK1R constitutes an attractive receptor for development of ligand-targeted imaging and… read more here.
Keywords: development ligand; ligand targeted; neurokinin receptor; receptor ... See more keywords
Ligand-Targeted Delivery of Photosensitizers for Cancer Treatment
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25225317
Abstract: Photodynamic therapy (PDT) is a promising cancer treatment which involves a photosensitizer (PS), light at a specific wavelength for PS activation and oxygen, which combine to elicit cell death. While the illumination required to activate… read more here.
Keywords: ligand targeted; cancer treatment; cancer; ligand ... See more keywords