Discovery of Environment-Sensitive Fluorescent Ligands of β-Adrenergic Receptors for Cell Imaging and NanoBRET Assay.
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DOI: 10.1021/acs.analchem.1c05646
Abstract: By fusing several environment-sensitive fluorophores to the pharmacophore mirabegron, a series of new fluorescent ligands for β-adrenergic receptors (β-ARs) were produced with a turn-on mechanism and high binding affinity to β-ARs efficiently. Compound L5 with… read more here.
Keywords: ligands adrenergic; fluorescent ligands; environment; environment sensitive ... See more keywords