Articles with "ligands estrogen" as a keyword



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Indazole-based ligands for estrogen-related receptor α as potential anti-diabetic agents.

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Published in 2017 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2017.07.015

Abstract: Estrogen-related receptor α (ERRα) is an orphan nuclear receptor that has been functionally implicated in the regulation of energy homeostasis. Herein is described the development of indazole-based N-alkylthiazolidenediones, which function in biochemical assays as selective… read more here.

Keywords: indazole based; based ligands; ligands estrogen; receptor ... See more keywords