Articles with "ligands targeting" as a keyword



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Fluorescent Ligands Targeting the Intracellular Allosteric Binding Site of the Chemokine Receptor CCR2.

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Published in 2022 at "ACS chemical biology"

DOI: 10.1021/acschembio.2c00263

Abstract: Fluorescently labeled ligands are versatile molecular tools to study G protein-coupled receptors (GPCRs) and can be used for a range of different applications, including bioluminescence resonance energy transfer (BRET) assays. Here, we report the structure-based… read more here.

Keywords: fluorescent ligands; ccr2; allosteric binding; targeting intracellular ... See more keywords