Articles with "ligase chip" as a keyword



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Specificity for latent C termini links the E3 ubiquitin ligase CHIP to caspases

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Published in 2019 at "Nature Chemical Biology"

DOI: 10.1038/s41589-019-0322-6

Abstract: Protein–protein interactions between E3 ubiquitin ligases and protein termini help shape the proteome. These interactions are sensitive to proteolysis, which alters the ensemble of cellular N and C termini. Here we describe a mechanism wherein… read more here.

Keywords: caspase; latent termini; ubiquitin ligase; termini ... See more keywords
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Conserved and Unique Roles of Chaperone-Dependent E3 Ubiquitin Ligase CHIP in Plants

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Published in 2021 at "Frontiers in Plant Science"

DOI: 10.3389/fpls.2021.699756

Abstract: Protein quality control (PQC) is essential for maintaining cellular homeostasis by reducing protein misfolding and aggregation. Major PQC mechanisms include protein refolding assisted by molecular chaperones and the degradation of misfolded and aggregated proteins using… read more here.

Keywords: ubiquitin ligase; chaperone dependent; conserved unique; ligase chip ... See more keywords