Highly multiplex and sensitive SNP genotyping method using a three‐color fluorescence‐labeled ligase detection reaction coupled with conformation‐sensitive CE
Sign Up to like & getrecommendations! Published in 2017 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201600369
Abstract: For the development of clinically useful genotyping methods for SNPs, accuracy, simplicity, sensitivity, and cost‐effectiveness are the most important criteria. Among the methods currently being developed for SNP genotyping technology, the ligation‐dependent method is considered… read more here.
Keywords: ligase detection; detection; method; detection reaction ... See more keywords
Detection of SNPs of T2DM susceptibility genes by a ligase detection reaction-fluorescent nanosphere technique.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2017.11.003
Abstract: OBJECTIVE To establish a high throughput, low cost, and simple nanotechnology-based method for the detection of single nucleotide polymorphism (SNP) loci in type 2 diabetes mellitus (T2DM). METHODS Multiplex ligase detection reaction (LDR) amplification was… read more here.
Keywords: ligase detection; t2dm; detection; t2dm susceptibility ... See more keywords