Selecting a DNA-Encoded Chemical Library against Non-immobilized Proteins Using a "Ligate-Cross-Link-Purify" Strategy.
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DOI: 10.1021/acs.bioconjchem.7b00343
Abstract: DNA-encoded chemical libraries (DELs) have recently emerged and become an important technology platform in biomedical research and drug discovery. DELs containing large numbers of compounds can be prepared and selected against biological targets to discover… read more here.
Keywords: ligate cross; immobilized proteins; dna encoded; proteins using ... See more keywords