Highly Precise Protein Semisynthesis through Ligation-Desulfurization Chemistry in Combination with Phenacyl Protection of Native Cysteines.
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DOI: 10.1007/978-1-0716-0434-2_17
Abstract: Semisynthesis of proteins via expressed protein ligation is a powerful tool to furnish full-length proteins carrying site-specific (posttranslational) modifications. The development of various β-mercapto amino acid building blocks coupled with ligation-desulfurization chemistry enabled further advances… read more here.
Keywords: protein; chemistry; ligation; native cysteines ... See more keywords