Cecal Ligation and Puncture.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1488-4_1
Abstract: Cecal ligation and puncture (CLP) is referred to as the "gold standard" rodent model for abdominal sepsis. CLP creates a continuously leaking, polymicrobial infectious focus in the abdomen. The abdominal cavity is opened under general… read more here.
Keywords: clp; cecal ligation; ligation puncture; biology ... See more keywords
Dauricine negatively regulates lipopolysaccharide- or cecal ligation and puncture-induced inflammatory response via NF-κB inactivation.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2019.03.018
Abstract: Acute lung injury (ALI) is a challenging clinical problem worldwide characterized by severe pulmonary inflammation. Dauricine, extracted from the root of traditional Chinese medicine Menispermum dauricum DC, is employed as anti-inflammatory herbs. In this study,… read more here.
Keywords: dauricine; ligation puncture; dauricine negatively; cecal ligation ... See more keywords
Peroxiredoxin 6 knockout aggravates cecal ligation and puncture‐induced acute lung injury
Sign Up to like & getrecommendations! Published in 2019 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2018.12.053
Abstract: Background: The aim of present study was to investigate the effects and mechanisms of peroxiredoxin (Prdx) 6 on cecal ligation and puncture (CLP) induced acute lung injury (ALI) in mice. Methods: The cecal of male… read more here.
Keywords: cecal ligation; ligation puncture; lung; injury ... See more keywords
Emodin attenuates acute lung injury in Cecal-ligation and puncture rats.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106626
Abstract: Acute lung injury (ALI) is a major cause of sepsis-induced acute respiratory failure. Emodin has been considered to play a protective role for acute lung edema in cecal ligation and puncture (CLP)-induced sepsis model. In… read more here.
Keywords: sepsis; cecal ligation; ligation puncture; emodin ... See more keywords
Induction of the NEK family of kinases in the lungs of mice subjected to cecal ligation and puncture model of sepsis.
Sign Up to like & getrecommendations! Published in 2021 at "Tissue barriers"
DOI: 10.1080/21688370.2021.1929787
Abstract: Endothelial barrier dysfunction (EBD) is the hallmark of Acute Respiratory Distress Syndrome (ARDS), a potentially lethal respiratory disorder associated with the COVID-19 - related deaths. Herein, we employed a cecal ligation and puncture (CLP) murine… read more here.
Keywords: sepsis; cecal ligation; ligation puncture; model sepsis ... See more keywords
Sex-Mediated Response to the Beta-Blocker Landiolol in Sepsis: An Experimental, Randomized Study
Sign Up to like & getrecommendations! Published in 2018 at "Critical Care Medicine"
DOI: 10.1097/ccm.0000000000003146
Abstract: Objectives: To investigate any gender effect of the beta-1 adrenergic blocker, landiolol, on cardiac performance and energy metabolism in septic rats, and to explore the expression of genes and proteins involved in this process. Design:… read more here.
Keywords: blocker landiolol; expression; cecal ligation; ligation puncture ... See more keywords
Use of Organ Dysfunction as A Primary Outcome Variable Following Cecal Ligation and Puncture: Recommendations for Future Studies.
Sign Up to like & getrecommendations! Published in 2019 at "Shock"
DOI: 10.1097/shk.0000000000001485
Abstract: Outcomes variables for research on sepsis have centered on mortality and changes in the host immune response. However, a recent task force (Sepsis-3) revised the definition of sepsis to "life-threatening organ dysfunction caused by a… read more here.
Keywords: sepsis; ligation puncture; organ dysfunction; human sepsis ... See more keywords
Astragalus polysaccharide protects sepsis model rats after cecum ligation and puncture
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.1020300
Abstract: To investigate the protective effect and mechanism of Astragalus polysaccharide (APS) on septic rats, the present project applied APS at concentrations of 400, 600, and 800 mg/kg/d to rats for prophylactic administration for 7 d,… read more here.
Keywords: cecum ligation; astragalus polysaccharide; ligation puncture; group ... See more keywords
Corrigendum: Candida Administration Worsens Cecal Ligation and Puncture-Induced Sepsis in Obese Mice Through Gut Dysbiosis Enhanced Systemic Inflammation, Impact of Pathogen-Associated Molecules From Gut Translocation and Saturated Fatty Acid
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.613095
Abstract: [This corrects the article DOI: 10.3389/fimmu.2020.561652.]. read more here.
Keywords: administration worsens; ligation puncture; candida administration; cecal ligation ... See more keywords
The Severity of Acute Kidney and Lung Injuries Induced by Cecal Ligation and Puncture Is Attenuated by Menthol: Role of Proliferating Cell Nuclear Antigen and Apoptotic Markers
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.904286
Abstract: Objective Sepsis-induced acute lung injury (ALI) and acute kidney injury (AKI) are major causes of mortality. Menthol is a natural compound that has anti-inflammatory and antioxidative actions. Since exaggerated inflammatory and oxidative stress are characteristics… read more here.
Keywords: sepsis; menthol; acute kidney; ligation puncture ... See more keywords
Sepsis Encephalopathy Is Partly Mediated by miR370-3p-Induced Mitochondrial Injury but Attenuated by BAM15 in Cecal Ligation and Puncture Sepsis Male Mice
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23105445
Abstract: BAM15 (a mitochondrial uncoupling agent) was tested on cecal ligation and puncture (CLP) sepsis mice with in vitro experiments. BAM15 attenuated sepsis as indicated by survival, organ histology (kidneys and livers), spleen apoptosis (activated caspase… read more here.
Keywords: sepsis; ligation puncture; brain; injury ... See more keywords