Structural Foundations of Potassium Selectivity in Channelrhodopsins
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DOI: 10.1128/mbio.03039-22
Abstract: Recently discovered microbial light-gated ion channels (channelrhodopsins) with a higher permeability for K+ than for Na+ (potassium-selective channelrhodopsins [kalium channelrhodopsins, or KCRs]) demonstrate an alternative K+ selectivity mechanism, unrelated to well-characterized “selectivity filters” of voltage-… read more here.
Keywords: potassium selective; selectivity; channelrhodopsins kcrs; selective channelrhodopsins ... See more keywords
Biophysical characterization of light-gated ion channels using planar automated patch clamp
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.976910
Abstract: Channelrhodopsins (ChRs) are proteins that guide phototaxis in protists and exhibit light-gated channel conductance when their genes are heterologously expressed in mammalian cells. ChRs are widely used as molecular tools to control neurons and cardiomyocytes… read more here.
Keywords: automated patch; patch clamp; light gated; patch ... See more keywords