A 'light-up' intercalator displacement assay for detection of triplex DNA stabilizers.
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DOI: 10.1039/c9cc08817b
Abstract: Here, we developed a coralyne-based, 'light-up' intercalator displacement assay to identify molecular stabilizers of triplex DNA using a sequence from a chromosomal breakpoint hotspot in the human c-MYC oncogene. Its potential to identify triplex DNA… read more here.
Keywords: intercalator displacement; displacement assay; triplex dna; assay detection ... See more keywords