High efficiency loading of micellar nanoparticles with a light switch for enzyme-induced rapid release of cargo.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials science"
DOI: 10.1039/d0bm01713b
Abstract: Polymeric nanoscale materials able to target and accumulate in the tumor microenvironment (TME) offer promising routes for a safer delivery of anticancer drugs. By reaching their targets before significant amounts of drug are released, such… read more here.
Keywords: high efficiency; efficiency loading; release; drug ... See more keywords
Cyclometalated platinum(II) complex as a selective light switch for G-quadruplex DNA.
Sign Up to like & getrecommendations! Published in 2023 at "Dalton transactions"
DOI: 10.1039/d3dt01188g
Abstract: Cyclometalated 1,3-bis(8-quinolyl) phenyl chloroplatinum(II) (Pt1) shows selective luminescence transduction of G-quadruplex binding over duplex DNA. The effect is enhanced on association with parallel and hybrid G-quadruplex structures over other topologies. The kinetics of binding are… read more here.
Keywords: dna; light switch; platinum complex; selective light ... See more keywords
A Green Light to Switch on Genes: Revisiting Trithorax on Plants
Sign Up to like & getrecommendations! Published in 2022 at "Plants"
DOI: 10.3390/plants12010075
Abstract: The Trithorax Group (TrxG) is a highly conserved multiprotein activation complex, initially defined by its antagonistic activity with the PcG repressor complex. TrxG regulates transcriptional activation by the deposition of H3K4me3 and H3K36me3 marks. According… read more here.
Keywords: trxg; light switch; green light; plants green ... See more keywords