RAC1 serves as a prognostic factor and correlated with immune infiltration in liver hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-024-05933-w
Abstract: Hepatocellular carcinoma (LIHC) has severe consequences due to late diagnosis and the lack of effective therapies. Currently, potential biomarkers for the diagnosis and prognosis of LIHC have not been systematically evaluated. Previous studies have reported… read more here.
Keywords: lihc; rac1 expression; tumor; infiltration ... See more keywords
Screening and Validation of a Carvacrol-Targeting Viability-Regulating Protein, SLC6A3, in Liver Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/3736104
Abstract: Background Liver hepatocellular carcinoma (LIHC) is the second leading cause of tumor-related death in the world. Carvacrol was also found to inhibit multiple cancer types. Here, we proposed that Carvacrol inhibited LIHC. Methods We used… read more here.
Keywords: carvacrol; hepatocellular carcinoma; lihc cells; lihc ... See more keywords
A Prognostic Model Based on NSUN3 Was Established to Evaluate the Prognosis and Response to Immunotherapy in Liver Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Mediators of Inflammation"
DOI: 10.1155/2023/6645476
Abstract: It is difficult for traditional therapies to further improve the prognosis of hepatocellular carcinoma (LIHC), and immunotherapy is considered to be a promising approach to overcome this dilemma. However, only a minority of patients benefit… read more here.
Keywords: hepatocellular carcinoma; prognosis; immunotherapy; lihc ... See more keywords
Development of a Starvation Response–Based Model and Its Application in Prognostic Assessment of Liver Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2025 at "Mediators of Inflammation"
DOI: 10.1155/mi/8828435
Abstract: Background: Hepatocellular carcinoma (LIHC) is a highly prevalent and poorly prognostic malignancy worldwide, and nutrient deprivation in the tumor microenvironment activates the starvation response in tumor cells. Starvation response-related genes (SRRGs) play critical roles in… read more here.
Keywords: starvation response; lihc; hepatocellular carcinoma; cell ... See more keywords
Abstract 883: Glutaminases expression and viral infection as potential prognostic factors in cervical, head and neck and liver cancers
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-883
Abstract: Human Papilloma virus (HPV)-associated Cervical squamous cell carcinoma (CESC-HPV(+)), HPV-associated Head and Neck squamous cell carcinoma (HNSCC-HPV(+)), and Hepatitis Virus B/C (HBV/HCV)-associated Liver hepatocellular carcinoma (LIHC-HBV(+)/LIHC-HCV(+)) present metabolic changes during viral transformation to adjust energy… read more here.
Keywords: hbv hcv; infection; hpv; lihc ... See more keywords
Elevated CircYthdc2 expression is correlated with aggressive features and poor progression-free survival in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2025 at "BMC Gastroenterology"
DOI: 10.1186/s12876-025-04231-0
Abstract: Liver hepatocellular carcinoma (LIHC) is a major contributor to cancer-related mortality. While early detection is crucial for improving outcomes, current diagnostic methods lack optimal sensitivity and specificity. Circular RNAs (circRNAs) have emerged as promising biomarkers… read more here.
Keywords: lihc; circythdc2 expression; hepatocellular carcinoma; circythdc2 ... See more keywords
LINC00638/hsa-miR-29b-3p axis-mediated high expression of CDCA4 correlates with tumor immune infiltration and hepatocellular carcinoma progression
Sign Up to like & getrecommendations! Published in 2023 at "Translational Cancer Research"
DOI: 10.21037/tcr-23-569
Abstract: Background This study sought to explore the role of cell division cycle-associated protein 4 (CDCA4) in liver hepatocellular carcinoma (LIHC) patients. Methods The RNA-sequencing raw count data and the respective clinical information of 33 different… read more here.
Keywords: expression; linc00638 hsa; hsa mir; lihc ... See more keywords
Linc00511 Indicates A Poor Prognosis Of Liver Hepatocellular Carcinoma
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DOI: 10.2147/ott.s228231
Abstract: Objective To uncover the specific function of linc00511 in the progression of liver hepatocellular carcinoma (LIHC) and the underlying mechanism. Patients and methods GEPIA dataset containing 9736 LIHC samples and 857 normal samples were downloaded… read more here.
Keywords: hepatocellular carcinoma; lihc; poor prognosis; liver hepatocellular ... See more keywords
Analysis and Validation of Tyrosine Metabolism-related Prognostic Features for Liver Hepatocellular Carcinoma Therapy.
Sign Up to like & getrecommendations! Published in 2024 at "Current medicinal chemistry"
DOI: 10.2174/0109298673290101240223074545
Abstract: AIMS To explore tyrosine metabolism-related characteristics in liver hepatocellular carcinoma (LIHC) and to establish a risk signature for the prognostic prediction of LIHC. Novel prognostic signatures contribute to the mining of novel biomarkers, which are… read more here.
Keywords: lihc; analysis; metabolism related; metabolism ... See more keywords
Comprehensive analysis of SLC43A2 on the tumor immune microenvironment and prognosis of liver hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.911378
Abstract: Background: Tumor cells outcompete T cells for methionine via overexpressing SLC43A2, causing T cells exhaustion. We explored the influence of SLC43A2 on tumor immune microenvironment (TIME), immune-related genes (IRGs) and the prognosis of liver hepatocellular… read more here.
Keywords: prognosis; slc43a2; tumor immune; lihc ... See more keywords
Prognostic Value and Immunological Role of KIFC1 in Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2021.799651
Abstract: As one of the members of the kinesin family, the role and potential mechanism of kinesin family member C1 (KIFC1) in the development of liver hepatocellular carcinoma (LIHC), especially in the immune infiltration, have not… read more here.
Keywords: kifc1; kifc1 mrna; hepatocellular carcinoma; role ... See more keywords