The human Vδ2+ T-cell compartment comprises distinct innate-like Vγ9+ and adaptive Vγ9- subsets
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-04076-0
Abstract: Vδ2+ T cells form the predominant human γδ T-cell population in peripheral blood and mediate T-cell receptor (TCR)-dependent anti-microbial and anti-tumour immunity. Here we show that the Vδ2+ compartment comprises both innate-like and adaptive subsets.… read more here.
Keywords: compartment comprises; like adaptive; human cell; adaptive subsets ... See more keywords
The distinct MHC‐unrestricted immunobiology of innate‐like and adaptive‐like human γδ T cell subsets—Nature's CAR‐T cells
Sign Up to like & getrecommendations! Published in 2020 at "Immunological Reviews"
DOI: 10.1111/imr.12928
Abstract: Distinct innate‐like and adaptive‐like immunobiological paradigms are emerging for human γδ T cells, supported by a combination of immunophenotypic, T cell receptor (TCR) repertoire, functional, and transcriptomic data. Evidence of the γδ TCR/ligand recognition modalities… read more here.
Keywords: adaptive like; like adaptive; biology; innate like ... See more keywords