Mechanism of Cellular Formation and In Vivo Seeding Effects of Hexameric β-Amyloid Assemblies.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular neurobiology"
DOI: 10.1007/s12035-021-02567-8
Abstract: The β-amyloid peptide (Aβ) is found as amyloid fibrils in senile plaques, a typical hallmark of Alzheimer's disease (AD). However, intermediate soluble oligomers of Aβ are now recognized as initiators of the pathogenic cascade leading… read more here.
Keywords: formation; pathology; hexameric; mechanism cellular ... See more keywords
Phosphorylation-Mediated Clearance of Amyloid-like Assemblies in Meiosis.
Sign Up to like & getrecommendations! Published in 2018 at "Developmental cell"
DOI: 10.1016/j.devcel.2018.04.001
Abstract: Amyloids are fibrous protein assemblies that are often described as irreversible and intrinsically pathogenic. However, yeast cells employ amyloid-like assemblies of the RNA-binding protein Rim4 to control translation during meiosis. Here, we show that multi-site… read more here.
Keywords: rim4; amyloid like; like assemblies; clearance ... See more keywords
Impact behaviour of plate-like assemblies made of new and existing interlocking bricks: A comparative study
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Impact Engineering"
DOI: 10.1016/j.ijimpeng.2018.02.008
Abstract: Abstract This paper presents an extensive numerical study on the impact behaviour of plate-like assemblies made of interlocking concrete bricks. In the proposed 3D finite element model, a damage based concrete model is employed with… read more here.
Keywords: behaviour plate; impact behaviour; assemblies made; like assemblies ... See more keywords