Gemcitabine‐induced epithelial‐mesenchymal transition‐like changes sustain chemoresistance of pancreatic cancer cells of mesenchymal‐like phenotype
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23090
Abstract: Growing body of evidence suggests that epithelial‐mesenchymal transition (EMT) is a critical process in tumor progression and chemoresistance in pancreatic cancer (PC). The aim of this study was to analyze the role of EMT‐like changes… read more here.
Keywords: phenotype; chemoresistance; cells mesenchymal; pancreatic cancer ... See more keywords
Calciphylaxis: looking for clues beyond skin biopsy
Sign Up to like & getrecommendations! Published in 2020 at "International Urology and Nephrology"
DOI: 10.1007/s11255-020-02424-y
Abstract: We read with great interest the recent article by Musso et al. about the differential diagnosis of calciphylaxis [1]. We would like to discuss recent developments in diagnosing calciphylaxis. Recently, nephrologists are moving away from… read more here.
Keywords: skin biopsies; skin biopsy; calciphylaxis; like changes ... See more keywords
Effect of reduced glutathione supplementation in semen extender on tyrosine phosphorylation and apoptosis like changes in frozen thawed Hariana bull spermatozoa.
Sign Up to like & getrecommendations! Published in 2017 at "Animal reproduction science"
DOI: 10.1016/j.anireprosci.2017.05.006
Abstract: To provide new insights into the mechanisms through which reduced glutathione (GSH) is able to protect spermatozoa, we tested the hypothesis that cryocapacitation and apoptosis like changes can contribute to the negative effect of freezing… read more here.
Keywords: spermatozoa; like changes; freezing thawing; apoptosis like ... See more keywords
Mifepristone attenuates depression-like changes induced by chronic central administration of interleukin-1β in rats
Sign Up to like & getrecommendations! Published in 2018 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2018.03.033
Abstract: HighlightsIL‐1&bgr; increased the levels of pro‐BDNF, but decreased GDNF and GFR&agr;1 in the amygdale.RU486 improved the depression‐like behaviors induced by IL‐1&bgr;.RU486 differently regulated the function of microglia and astrocyte. ABSTRACT Increased proinflammatory cytokines, such as… read more here.
Keywords: depression; gfr agr; bgr; changes induced ... See more keywords
O017 Dupuytren's disease (DD): WNT4 knockdown in normal skin fibroblasts leads to ‘DD-like’ changes in the transcriptome
Sign Up to like & getrecommendations! Published in 2023 at "British Journal of Surgery"
DOI: 10.1093/bjs/znad101.017
Abstract: Dupuytren's disease (DD), a fibro-proliferative disorder of unknown aetiology, affects the palm and is characterised by progressive fibrosis, thickening of palmar fascia, and excess collagen deposition. Patients present with nodules, causing flexion deformity in ∼50%,… read more here.
Keywords: like changes; skin; changes transcriptome; skin fibroblasts ... See more keywords
Experimental functional shift-induced osteoarthritis-like changes at the TMJ and altered integrin expression in a rat model.
Sign Up to like & getrecommendations! Published in 2022 at "Annals of the New York Academy of Sciences"
DOI: 10.1111/nyas.14741
Abstract: Mandibular deviation affects the biomechanical environment of the temporomandibular joint (TMJ) and causes thinning of cartilage on the deviated side. We aimed to evaluate, using a rat model, the effect of mandibular functional deviation on… read more here.
Keywords: functional shift; rat model; like changes; experimental functional ... See more keywords
Recurrent abdominal pain, vomiting, velvet-like changes in the small intestine in a patient with multiple acyl-CoA dehydrogenase deficiency: a case report.
Sign Up to like & getrecommendations! Published in 2021 at "Translational pediatrics"
DOI: 10.21037/tp-20-253
Abstract: Multiple acyl-CoA dehydrogenase deficiency (MADD) is an inborn error of metabolism in fatty acid oxidation. We described an unusual case of recurrent vomiting and abdominal pain in a child with MADD, presenting with velvet-like changes… read more here.
Keywords: velvet like; changes small; case; like changes ... See more keywords
Osteoarthritis-Like Changes in Bardet–Biedl Syndrome Mutant Ciliopathy Mice (Bbs1M390R/M390R): Evidence for a Role of Primary Cilia in Cartilage Homeostasis and Regulation of Inflammation
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2018.00708
Abstract: Osteoarthritis (OA) is a debilitating inflammation related disease characterized by joint pain and effusion, loss of mobility, and deformity that may result in functional joint failure and significant impact on quality of life. Once thought… read more here.
Keywords: inflammation; primary cilia; bbs1m390r m390r; changes bardet ... See more keywords