Design of Perfused PTFE Vessel-Like Constructs for In Vitro Applications.
Sign Up to like & getrecommendations! Published in 2021 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202100016
Abstract: Tissue models mimic the complex 3D structure of human tissues, which allows the study of pathologies and the development of new therapeutic strategies. The introduction of perfusion overcomes the diffusion limitation and enables the formation… read more here.
Keywords: like constructs; design perfused; vessel like; tissue models ... See more keywords
Permeable hollow 3D tissue-like constructs engineered by on-chip hydrodynamic-driven assembly of multicellular hierarchical micromodules.
Sign Up to like & getrecommendations! Published in 2020 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2020.06.010
Abstract: Engineered three-dimensional (3D) microtissues that recapitulate in vivo tissue morphology and microvessel lumens have shown significant potential in drug screening and regenerative medicine. Although microfluidic-based techniques have been developed for bottom-up assembly of 3D tissue… read more here.
Keywords: like constructs; permeable hollow; hierarchical micromodules; tissue ... See more keywords
Engineering pre-vascularized bone-like tissue from human mesenchymal stem cells through simulating endochondral ossification.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2022.121451
Abstract: Currently, most in vitro engineered bone tissues do not contain viable blood vessel systems, so the vascularization depends on post-implantation angiogenesis from the host, which is often insufficient for repairing large bone defects. In this… read more here.
Keywords: like constructs; bone; bone like; hbmscs ... See more keywords
Development of Biomimetic Hepatic Lobule-Like Constructs on Silk-Collagen Composite Scaffolds for Liver Tissue Engineering
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.940634
Abstract: Constructing an engineered hepatic lobule-mimetic model is challenging owing to complicated lobular architecture and crucial hepatic functionality. Our previous study has demonstrated the feasibility of using silk fibroin (SF) scaffolds as functional templates for engineering… read more here.
Keywords: like constructs; lobule; lobule like; composite scaffolds ... See more keywords