Development of a Transcriptional Activator‐Like Effector Protein to Accurately Discriminate Single Nucleotide Difference
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DOI: 10.1002/cbic.202200486
Abstract: Transcriptional activator‐like effector (TALE), a DNA‐binding protein, is widely used in genome editing. However, the recognition of the target sequence by the TALE is adversely affected by the number of mismatches. Therefore, the association constant… read more here.
Keywords: activator like; nucleotide difference; transcriptional activator; nucleotide ... See more keywords
A MIF-like effector suppresses plant immunity and facilitates nematode parasitism by interacting with plant annexins
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DOI: 10.1093/jxb/erz348
Abstract: The plant-parasitic nematode Meloidogyne incognita secretes MIF-like proteins into plant tissues, and MiMIF-2 interacts with two plant annexins to suppress plant immune responses and promote parasitism. read more here.
Keywords: plant; effector suppresses; mif like; like effector ... See more keywords
Binding of the transcription activator-like effector augments transcriptional regulation by another transcription factor
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DOI: 10.1093/nar/gkac454
Abstract: Abstract DNA transcription is regulated by a range of diverse mechanisms and primarily by transcription factors that recruit the RNA polymerase complex to the promoter region on the DNA. Protein binding to DNA at nearby… read more here.
Keywords: transcription activator; dna; transcription; transcriptional regulation ... See more keywords
Cell death‐inducing DFF45‐like effector C gene silencing alleviates pulmonary vascular remodeling in a type 2 diabetic rat model
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DOI: 10.1111/jdi.12768
Abstract: Cell death‐inducing DFF45‐like effector C (CIDEC) was proven to be closely associated with the development of insulin resistance and metabolic syndrome. We aimed to investigate whether CIDEC gene silencing could alleviate pulmonary vascular remodeling in… read more here.
Keywords: dff45 like; gene silencing; cell death; inducing dff45 ... See more keywords