Chemokine‐like factor 1 (CKLF1) aggravates neointimal hyperplasia through activating the NF‐κB /VCAM‐1 pathway
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DOI: 10.1002/2211-5463.12942
Abstract: Neointimal hyperplasia (NIH) is a complicated inflammatory process contributing to vascular restenosis. The present study aimed to explore whether chemokine‐like factor 1 (CKLF1) aggravates NIH via the nuclear factor‐kappa B (NF‐κB)/vascular cell adhesion molecule‐1 (VCAM‐1)… read more here.
Keywords: vcam pathway; cklf1; like factor; chemokine like ... See more keywords
miR‐324‐5p promotes adipocyte differentiation and lipid droplet accumulation by targeting Krueppel‐like factor 3 (KLF3)
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DOI: 10.1002/jcp.29652
Abstract: miRNAs, a kind of noncoding small RNA, play a significant role in adipose differentiation. In this study, we explored the effect of miR‐324‐5p in adipose differentiation, and found that miR‐324‐5p could promote adipocytes differentiation and… read more here.
Keywords: accumulation; factor klf3; like factor; differentiation ... See more keywords
Backbone 1H, 13C, and 15N NMR resonance assignments of the Krüppel-like factor 4 activation domain
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DOI: 10.1007/s12104-017-9727-x
Abstract: Krüppel-like factor 4 (KLF4) is a transcription factor involved in diverse biological processes, including development, cellular differentiation and proliferation, and maintenance of tissue homeostasis. KLF4 has also been associated with disease states, such as cardiovascular… read more here.
Keywords: ppel like; like factor; activation domain; activation ... See more keywords
New theca-cell marker insulin-like factor 3 is associated with premature ovarian insufficiency.
Sign Up to like & getrecommendations! Published in 2020 at "Fertility and sterility"
DOI: 10.1016/j.fertnstert.2020.08.005
Abstract: OBJECTIVE To characterize circulating insulin-like factor 3 (INSL3) in different stages of ovarian insufficiency and its role in the evaluation of premature ovarian insufficiency (POI). DESIGN Retrospective cohort study. SETTING University-based center for reproductive medicine.… read more here.
Keywords: insl3; like factor; insulin like; ovarian insufficiency ... See more keywords
Kruppel-like factor 4-dependent Staufen1-mediated mRNA decay regulates cortical neurogenesis
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DOI: 10.1038/s41467-017-02720-9
Abstract: Kruppel-like factor 4 (Klf4) is a zinc-finger-containing protein that plays a critical role in diverse cellular physiology. While most of these functions attribute to its role as a transcription factor, it is postulated that Klf4… read more here.
Keywords: kruppel like; klf4; like factor; neurogenesis ... See more keywords
Eosinophil function in adipose tissue is regulated by Krüppel-like factor 3 (KLF3)
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-16758-9
Abstract: The conversion of white adipocytes to thermogenic beige adipocytes represents a potential mechanism to treat obesity and related metabolic disorders. However, the mechanisms involved in converting white to beige adipose tissue remain incompletely understood. Here… read more here.
Keywords: factor klf3; like factor; tissue; ppel like ... See more keywords
The Krüppel-Like Factor 15-NFATc1 Axis Ameliorates Podocyte Injury: A Novel Rationale for Using Glucocorticoids in Proteinuria Diseases.
Sign Up to like & getrecommendations! Published in 2020 at "Clinical science"
DOI: 10.1042/cs20200075
Abstract: Podocyte injury and loss contribute to proteinuria, glomerulosclerosis and eventually kidney failure. Recent studies have demonstrated that the loss of Kruppel-like factor 15 (KLF15) in podocytes increases the susceptibility to injury; however, the mechanism underlying… read more here.
Keywords: klf15; like factor; nfatc1 axis; podocyte injury ... See more keywords
Chemokine-like factor-like MARVEL transmembrane domain-containing family in autoimmune diseases
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DOI: 10.1097/cm9.0000000000000747
Abstract: Abstract The chemokine-like factor (CKLF)-like MARVEL transmembrane domain-containing family (CMTM) is widely expressed in the immune system. Abnormal expression of CMTM is associated with the development of various diseases. This article summarizes the relevant research… read more here.
Keywords: marvel transmembrane; chemokine like; like factor; like marvel ... See more keywords
Loss of Krüppel‐like factor 9 facilitates stemness in ovarian cancer ascites‐derived multicellular spheroids via Notch1/slug signaling
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DOI: 10.1111/cas.15100
Abstract: The ascites that develops in advanced OC, both at diagnosis and upon recurrence, is a rich source of multicellular spheroids/aggregates (MCSs/MCAs), which are the major seeds of tumor cell dissemination within the abdominal cavity. However,… read more here.
Keywords: like factor; ppel like; ascites derived; cancer ... See more keywords
Kruppel‐like factor 15 regulates fuel switching between glucose and fatty acids in brown adipocytes
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DOI: 10.1111/jdi.13511
Abstract: Brown adipose tissue (BAT) utilizes large amounts of fuel for thermogenesis, but the mechanism by which fuel substrates are switched in response to changes in energy status is poorly understood. We have now investigated the… read more here.
Keywords: kruppel like; like factor; regulates fuel; factor regulates ... See more keywords
A DINOFLAGELLATE TBP‐LIKE FACTOR ACTIVATES TRANSCRIPTION FROM A TTTT‐BOX IN YEAST
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Phycology"
DOI: 10.1111/jpy.13243
Abstract: Dinoflagellates do not have a typical TATA‐binding protein (TBP), a subunit of the general transcription factor TFIID complex. Instead, they have a TBP‐like factor (TLF) that has been shown to bind TTTT instead of TATA… read more here.
Keywords: tbp like; like factor; factor; box ... See more keywords