Insights into receptor-like kinases-activated downstream events in plants
Sign Up to like & getrecommendations! Published in 2018 at "Science China Life Sciences"
DOI: 10.1007/s11427-018-9440-1
Abstract: Unlike vertebrates that have the circulating immune system, plants have evolved an efficient innate immune system to defend against invading pathogens. At cellular level, the plant innate immunity primarily relies on plasma membranelocalized receptor-like kinases… read more here.
Keywords: rlks mediated; kinase; receptor like; activation ... See more keywords
miR393 regulation of lectin receptor-like kinases associated with LPS perception in Arabidopsis thaliana.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.03.170
Abstract: microRNAs regulate dynamic aspects of innate immunity in Arabidopsis thaliana in response to lipopolysaccharides. Lectin-domain receptor-like kinases function as surveillance proteins and miR393 targets transcripts of an L-type LecRK (LECRK-V.7, At3g59740). This study investigated miR393… read more here.
Keywords: arabidopsis thaliana; perception; mir393; receptor like ... See more keywords
Tousled-Like Kinases Suppress Innate Immune Signaling Triggered by Alternative Lengthening of Telomeres
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DOI: 10.1016/j.celrep.2020.107983
Abstract: Summary The Tousled-like kinases 1 and 2 (TLK1/2) control histone deposition through the ASF1 histone chaperone and influence cell cycle progression and genome maintenance, yet the mechanisms underlying TLK-mediated genome stability remain uncertain. Here, we… read more here.
Keywords: kinases suppress; alternative lengthening; like kinases; innate immune ... See more keywords
Differential requirements for Tousled-like kinases 1 and 2 in mammalian development
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DOI: 10.1038/cdd.2017.108
Abstract: The regulation of chromatin structure is critical for a wide range of essential cellular processes. The Tousled-like kinases, TLK1 and TLK2, regulate ASF1, a histone H3/H4 chaperone, and likely other substrates, and their activity has… read more here.
Keywords: mammalian development; tlk2; like kinases; tousled like ... See more keywords
Plasma Membrane-Associated Receptor-like Kinases Relocalize to Plasmodesmata in Response to Osmotic Stress1[OPEN]
Sign Up to like & getrecommendations! Published in 2019 at "Plant Physiology"
DOI: 10.1104/pp.19.00473
Abstract: Osmotic stress triggers rapid reorganization of the receptor kinases QSK1 and IMK2 at plasmodesmata and induces callose-mediated plasmodesmata closure. Plasmodesmata act as key elements in intercellular communication, coordinating processes related to plant growth, development, and… read more here.
Keywords: like kinases; response; stress; response osmotic ... See more keywords
A pair of G-type lectin receptor-like kinases modulate nlp20-mediated immune responses by coupling to RLP23 receptor complex.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of integrative plant biology"
DOI: 10.1111/jipb.13449
Abstract: Plant cells recognize microbial patterns with the plasma-membrane-localized pattern-recognition receptors (PRRs) consisting mainly of receptor kinases (RKs) and receptor-like proteins (RLPs). RKs, such as bacterial flagellin receptor FLS2, and their downstream signaling components have been… read more here.
Keywords: receptor like; mediated immune; like kinases; receptor ... See more keywords
Molecular dialogues between viruses and receptor‐like kinases in plants
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DOI: 10.1111/mpp.12812
Abstract: Summary Receptor‐like kinases (RLKs) play a prominent role in the interaction between plants and extracellular pathogens. Intriguingly, in the past few years several studies have demonstrated that a number of RLKs influence plant susceptibility to… read more here.
Keywords: viruses receptor; molecular dialogues; receptor like; like kinases ... See more keywords
Structural Basis for the Selective Inhibition of Cdc2-Like Kinases by CX-4945
Sign Up to like & getrecommendations! Published in 2019 at "BioMed Research International"
DOI: 10.1155/2019/6125068
Abstract: Cdc2-like kinases (CLKs) play a crucial role in the alternative splicing of eukaryotic pre-mRNAs through the phosphorylation of serine/arginine-rich proteins (SR proteins). Dysregulation of this processes is linked with various diseases including cancers, neurodegenerative diseases,… read more here.
Keywords: structural basis; cdc2 like; clk2; basis selective ... See more keywords
Abstract 5336: Discovery of a novel activin receptor-like kinases (ALKs) inhibitor targeting TGF-β signaling pathways
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-5336
Abstract: Introduction: Transforming growth factor β (TGF-β) plays a key role in promoting tumor progression mainly through facilitating angiogenesis, epithelial-mesenchymal transition (EMT) and also inducing immunosuppression in tumor microenvironment, allowing cancer cells to escape immune surveillance.… read more here.
Keywords: kinases alks; receptor like; activin receptor; like kinases ... See more keywords
Novel Signaling Interface Constituted with Membrane Receptor-Like Kinases Emerged from the Study of Interaction and Transphosphorylation of BRI1 and BAK1.
Sign Up to like & getrecommendations! Published in 2017 at "Current topics in medicinal chemistry"
DOI: 10.2174/1568026617666170414144145
Abstract: BRI1 and BAK1 are Receptor-Like Kinases (RLKs), one of the largest gene families in plants participating in various cell signal transduction from cell surface to cytoplasm with oligomerization and phosphorylation to regulate plant growth, development,… read more here.
Keywords: bri1 bak1; bri1; receptor like; like kinases ... See more keywords
Versatile Physiological Functions of Plant GSK3-Like Kinases
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DOI: 10.3390/genes12050697
Abstract: The plant glycogen synthase kinase 3 (GSK3)-like kinases are highly conserved protein serine/threonine kinases that are grouped into four subfamilies. Similar to their mammalian homologs, these kinases are constitutively active under normal growth conditions but… read more here.
Keywords: gsk3 like; plant; physiological functions; plant gsk3 ... See more keywords