C1Q labels a highly aggressive macrophage-like leukemia population indicating extramedullary infiltration and relapse.
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DOI: 10.1182/blood.2022017046
Abstract: Extramedullary infiltration (EMI) is a concomitant manifestation that may indicate poor outcome of acute myeloid leukemia (AML). The underlying mechanism remains poorly understood and therapeutic options are limited. Here, we employed single-cell RNA sequencing on… read more here.
Keywords: infiltration; c1q; like leukemia; macrophage like ... See more keywords