Probing conformational transitions towards mutagenic Watson–Crick-like G·T mismatches using off-resonance sugar carbon R1ρ relaxation dispersion
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DOI: 10.1007/s10858-020-00337-7
Abstract: NMR off-resonance R 1ρ relaxation dispersion measurements on base carbon and nitrogen nuclei have revealed that wobble G·T/U mismatches in DNA and RNA duplexes exist in dynamic equilibrium with short-lived, low-abundance, and mutagenic Watson–Crick-like conformations.… read more here.
Keywords: watson crick; crick like; sugar; like mismatches ... See more keywords