Peptidyl Virus-Like Nanovesicles as Reconfigurable "Trojan Horse" for Targeted siRNA Delivery and Synergistic Inhibition of Cancer Cells.
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DOI: 10.1002/smll.202204959
Abstract: The self-assembly of peptidyl virus-like nanovesicles (pVLNs) composed of highly ordered peptide bilayer membranes that encapsulate the small interfering RNA (siRNA) is reported. The targeting and enzyme-responsive sequences on the bilayer's surface allow the pVLNs… read more here.
Keywords: cancer; like nanovesicles; reconfigurable trojan; peptidyl virus ... See more keywords
Current progress of plant-derived exosome-like nanovesicles on the regulation of osteoporosis and osteoarthritis
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DOI: 10.1080/07853890.2025.2549524
Abstract: Abstract Osteoporosis (OP) and osteoarthritis (OA) are clinically common chronic orthopedic diseases. With the aging of the global population, OP and OA pose a serious threat to human health. Exosomes are nanoscale vesicles secreted by… read more here.
Keywords: current progress; plant derived; like nanovesicles; osteoporosis osteoarthritis ... See more keywords
Momordica charantia L.-derived exosome-like nanovesicles stabilize p62 expression to ameliorate doxorubicin cardiotoxicity
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DOI: 10.1186/s12951-024-02705-z
Abstract: Doxorubicin (DOX) is a first-line chemotherapeutic drug for various malignancies that causes cardiotoxicity. Plant-derived exosome-like nanovesicles (P-ELNs) are growing as novel therapeutic agents. Here, we investigated the protective effects in DOX cardiotoxicity of ELNs from… read more here.
Keywords: derived exosome; cardiotoxicity; exosome like; like nanovesicles ... See more keywords
Hypericum Perforatum-Derived Exosomes-Like Nanovesicles: A Novel Natural Photosensitizer for Effective Tumor Photodynamic Therapy
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DOI: 10.2147/ijn.s510339
Abstract: Background Natural photosensitizers hold potential for photodynamic therapy (PDT) but are often limited by poor visible light absorption. Plant-derived exosome-like nanovesicles offer an innovative platform for enhancing photosensitizer performance. Methods Hypericum perforatum-derived nanovesicles (HPDENs) were… read more here.
Keywords: therapy; like nanovesicles; perforatum derived; tumor ... See more keywords
Plant-Derived Exosome-Like Nanovesicles: A Novel Strategy for Targeted Oral Therapy in Ulcerative Colitis
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DOI: 10.2147/ijn.s536056
Abstract: Abstract Ulcerative colitis (UC) is a chronic inflammatory bowel disease, the incidence of which continues to rise globally, and existing therapeutic options are limited by low drug bioavailability and systemic side effects. In this study,… read more here.
Keywords: derived exosome; plant; exosome like; plant derived ... See more keywords
Extracellular vesicles and exosome-like nanovesicles as pioneering oral drug delivery systems
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2023.1307878
Abstract: As extracellular vesicle (EV)-based nanotechnology has developed rapidly, it has made unprecedented opportunities for nanomedicine possible. EVs and exosome-like nanovesicles (ELNVs) are natural nanocarriers with unique structural, compositional, and morphological characteristics that provide excellent physical,… read more here.
Keywords: extracellular vesicles; exosome like; delivery; like nanovesicles ... See more keywords
Poria cocos-Derived Exosome-like Nanovesicles Alleviate Metabolic Dysfunction-Associated Fatty Liver Disease by Promoting Mitophagy and Inhibiting NLRP3 Inflammasome Activation
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DOI: 10.3390/ijms26052253
Abstract: Metabolic dysfunction-associated fatty liver disease (MAFLD) affects approximately one-quarter of the world’s adult population, and no effective therapeutic drugs are available. Poria cocos is a fungus used as a herb and food nutrient for centuries… read more here.
Keywords: poria cocos; exosome like; like nanovesicles; mafld ... See more keywords