DOPG small unilamellar vesicles function as nano-carriers targeting the clustered lectin-like oxidized LDL receptor (LOX-1) on the cell surface
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2019.03.014
Abstract: Abstract The lectin-like oxidized low-density lipoprotein (OxLDL) receptor (LOX-1) is the primary OxLDL receptor of vascular endothelial cells. OxLDL binding to LOX-1 promotes atherogenesis by upregulating LOX-1 expression to further sensitize cells against OxLDL. In… read more here.
Keywords: surface; lectin like; like oxidized; receptor ... See more keywords
Role of Lectin-like Oxidized LDL Receptor-1 and Syncytiotrophoblast Extracellular Vesicles in the Vascular Reactivity of Mouse Uterine Arteries During Pregnancy
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DOI: 10.1038/s41598-020-63205-2
Abstract: Vascular complications in pregnancy (e.g. preeclampsia) are a major source of maternal and foetal morbidity and mortality, and may be due to excessive release of placental syncytiotrophoblast-derived extracellular vesicles (STBEVs) into the maternal circulation. Increased… read more here.
Keywords: extracellular vesicles; like oxidized; oxidized ldl; receptor ... See more keywords
Lectin-like oxidized low-density lipoprotein receptor 1 attenuates pneumonia-induced lung injury
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DOI: 10.1172/jci.insight.149955
Abstract: Identifying host factors that contribute to pneumonia incidence and severity are of utmost importance to guiding the development of more effective therapies. Lectin-like oxidized low-density lipoprotein receptor 1 (LOX-1, encoded by OLR1) is a scavenger… read more here.
Keywords: lectin like; lung; low density; like oxidized ... See more keywords