Branched short elastin‐like peptides with temperature responsiveness obtained by EDTA‐mediated multimerization
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Peptide Science"
DOI: 10.1002/psc.3449
Abstract: Elastin‐like peptides (ELPs) exhibit a reversible phase transition, known as coacervation, triggered by temperature changes. This property makes them useful as stimuli‐responsive molecular materials for various applications. Among ELPs, short peptide chain lengths have some… read more here.
Keywords: like peptides; elastin like; temperature; multimerization ... See more keywords
Role of glucagon-like peptides in inflammatory bowel diseases—current knowledge and future perspectives
Sign Up to like & getrecommendations! Published in 2019 at "Naunyn-Schmiedeberg's Archives of Pharmacology"
DOI: 10.1007/s00210-019-01698-z
Abstract: Inflammatory bowel diseases (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), are chronic, relapsing, intestinal inflammatory disorders with complex and yet unrevealed pathogenesis in which genetic, immunological, and environmental factors play a role. Nowadays,… read more here.
Keywords: glucagon like; inflammatory bowel; current knowledge; bowel diseases ... See more keywords
Identification of Rubisco anxiolytic-like peptides (rALPs) by comprehensive analysis of spinach green leaf protein digest.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.09.195
Abstract: Rubisco, an enzyme for photosynthetic carbon dioxide fixation, is a major green leaf protein and known as the most abundant protein on the Earth. We found that Rubisco digested mimicking gastrointestinal enzymatic conditions exhibited anxiolytic-like… read more here.
Keywords: protein; ralp ralp; ralp; green leaf ... See more keywords
Increased Akt signaling in the fat body of Anopheles stephensi extends lifespan and increases lifetime fecundity through modulation of insulin-like peptides.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of insect physiology"
DOI: 10.1016/j.jinsphys.2019.103932
Abstract: Insulin-like peptides (ILPs) and the insulin/insulin-like growth factor 1 signaling (IIS) cascade regulate numerous physiological functions, including lifespan, reproduction, immunity, and metabolism, in diverse eukaryotes. We previously demonstrated that in female Anopheles stephensi and Aedes… read more here.
Keywords: fat body; lifetime fecundity; insulin like; like peptides ... See more keywords
Isolation and characterization of FMRFamide-like peptides in the venoms of solitary sphecid wasps
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DOI: 10.1016/j.peptides.2021.170575
Abstract: Purification of small peptide components in the venoms of the solitary sphecid wasps, Sphex argentatus argentatus and Isodontia harmandi, led to the isolation of several major peptides. Analysis of MS/MS spectra by MALDI-TOF/TOF revealed the… read more here.
Keywords: sphecid wasps; fmrfamide like; solitary sphecid; venoms solitary ... See more keywords
Insulin signaling in Drosophila melanogaster mediates Aβ toxicity
Sign Up to like & getrecommendations! Published in 2019 at "Communications Biology"
DOI: 10.1038/s42003-018-0253-x
Abstract: Alzheimer’s disease (AD) and diabetes are clinically positively correlated. However, the connection between them is not clarified. Here, using Drosophila as a model system, we show that reducing insulin signaling can effectively suppress the toxicity… read more here.
Keywords: insulin; insulin like; toxicity; signaling drosophila ... See more keywords
Insulin-Like Peptides and Cross-Talk With Other Factors in the Regulation of Insect Metabolism
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2021.701203
Abstract: The insulin-like peptide (ILP) and insulin-like growth factor (IGF) signalling pathways play a crucial role in the regulation of metabolism, growth and development, fecundity, stress resistance, and lifespan. ILPs are encoded by multigene families that… read more here.
Keywords: insulin; metabolism; insulin like; insect metabolism ... See more keywords
Temporin-Like Peptides Show Antimicrobial and Anti-Biofilm Activities against Streptococcus mutans with Reduced Hemolysis
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25235724
Abstract: In our previous study, temporin-GHaR (GHaR) showed potent antimicrobial activity with strong hemolytic toxicity. To overcome its weakness, we designed GHaR6R, GHaR7R, GHaR8R, GHaR9R, and GHaR9W by changing the number of positive charges and the… read more here.
Keywords: temporin like; show antimicrobial; peptides show; derived peptides ... See more keywords
Anti-Fungal Hevein-like Peptides Biosynthesized from Quinoa Cleavable Hololectins
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DOI: 10.3390/molecules26195909
Abstract: Chitin-binding hevein-like peptides (CB-HLPs) belong to a family of cysteine-rich peptides that play important roles in plant stress and defense mechanisms. CB-HLPs are ribosomally synthesized peptides that are known to be bioprocessed from the following… read more here.
Keywords: anti fungal; family; chitin binding; cleavable hololectins ... See more keywords
Self-Organization Dynamics of Collagen-like Peptides Crosslinking Is Driven by Rose-Bengal-Mediated Electrostatic Bridges
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14061148
Abstract: The present work focuses on the computational study of the structural micro-organization of hydrogels based on collagen-like peptides (CLPs) in complex with Rose Bengal (RB). In previous studies, these hydrogels computationally and experimentally demonstrated that… read more here.
Keywords: like peptide; rose bengal; like peptides; organization ... See more keywords
Discovery of Surfactant-Like Peptides from a Phage-Displayed Peptide Library
Sign Up to like & getrecommendations! Published in 2020 at "Viruses"
DOI: 10.3390/v12121442
Abstract: Peptides with specific affinities for various materials have been identified in the past three decades and utilized in materials science and engineering. A peptide’s capability to specifically interact with materials is not naturally derived but… read more here.
Keywords: peptides phage; surfactant like; displayed peptide; peptide library ... See more keywords