Articles with "like phenotypes" as a keyword



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Electrical Differentiation of Mesenchymal Stem Cells into Schwann‐Cell‐Like Phenotypes Using Inkjet‐Printed Graphene Circuits

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Published in 2017 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.201601087

Abstract: Graphene-based materials (GBMs) have displayed tremendous promise for use as neurointerfacial substrates as they enable favorable adhesion, growth, proliferation, spreading, and migration of immobilized cells. This study reports the first case of the differentiation of… read more here.

Keywords: like phenotypes; differentiation mesenchymal; schwann cell; differentiation ... See more keywords
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Apelin-13 Upregulates BDNF Against Chronic Stress-induced Depression-like Phenotypes by Ameliorating HPA Axis and Hippocampal Glucocorticoid Receptor Dysfunctions

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Published in 2018 at "Neuroscience"

DOI: 10.1016/j.neuroscience.2018.08.018

Abstract: Localization of apelin and its receptor APJ in limbic structures such as the hippocampus suggests potential involvement of apelin/APJ signaling in stress-related emotional responses. We have recently reported that apelin-13 exerts antidepressant-like actions in acute… read more here.

Keywords: like phenotypes; apelin; stress; receptor ... See more keywords
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Elevating expression of MeCP2 T158M rescues DNA binding and Rett syndrome–like phenotypes

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Published in 2017 at "Journal of Clinical Investigation"

DOI: 10.1172/jci90967

Abstract: Mutations in the X-linked gene encoding methyl-CpG–binding protein 2 (MeCP2) cause Rett syndrome (RTT), a neurological disorder affecting cognitive development, respiration, and motor function. Genetic restoration of MeCP2 expression reverses RTT-like phenotypes in mice, highlighting… read more here.

Keywords: like phenotypes; mecp2 t158m; rett syndrome; mecp2 ... See more keywords
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Ingestion of Lactobacillus intestinalis and Lactobacillus reuteri causes depression- and anhedonia-like phenotypes in antibiotic-treated mice via the vagus nerve

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Published in 2020 at "Journal of Neuroinflammation"

DOI: 10.1186/s12974-020-01916-z

Abstract: The brain–gut–microbiota axis plays a role in the pathogenesis of stress-related disorders such as depression. In this study, we examined the effects of fecal microbiota transplantation (FMT) in mice with antibiotic-treated microbiota depletion. The fecal… read more here.

Keywords: antibiotic treated; like phenotypes; treated mice; anhedonia like ... See more keywords
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Renieramycin M Attenuates Cancer Stem Cell-like Phenotypes in H460 Lung Cancer Cells.

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Published in 2017 at "Anticancer research"

DOI: 10.21873/anticanres.11355

Abstract: BACKGROUND/AIM Cancer stem cells (CSCs) are a subpopulation of cancer cells that possess self-renewal and differentiation capacities. CSCs contribute to drug-resistance, cancer recurrence and metastasis, thus development of CSC-targeted therapeutic strategies has recently received significant… read more here.

Keywords: cancer stem; like phenotypes; cancer cells; cancer ... See more keywords

A Mild Form of COG5 Defect Showing Early-Childhood-Onset Friedreich's-Ataxia-Like Phenotypes with Isolated Cerebellar Atrophy

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Published in 2017 at "Journal of Korean Medical Science"

DOI: 10.3346/jkms.2017.32.11.1885

Abstract: Progressive cerebellar ataxias are rare diseases during childhood, especially under 6 years of age. In a single family, three affected siblings exhibited Friedreich's-ataxia-like phenotypes before 2 years of age. They had progressive cerebellar atrophy, intellectual… read more here.

Keywords: like phenotypes; cog5; friedreich ataxia; cog5 defect ... See more keywords
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Insulin Elevates ID2 Expression in Trophoblasts and Aggravates Preeclampsia in Obese ASB4-Null Mice

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Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24032149

Abstract: Obesity is a risk factor for preeclampsia. We investigated how obesity influences preeclampsia in mice lacking ankyrin-repeat-and-SOCS-box-containing-protein 4 (ASB4), which promotes trophoblast differentiation via degrading the inhibitor of DNA-binding protein 2 (ID2). Asb4−/− mice on… read more here.

Keywords: elevates id2; insulin elevates; like phenotypes; mice ... See more keywords