MiR-101-3p inhibits MTX-mediated HMGB1 release and reduces recruitment and M1-like polarization of macrophages through the UBE2D1/KAT2B pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.22987
Abstract: The results of recent studies have shown that miRNAs play a vital role in tumor microenvironment during Methotrexate (MTX) chemotherapy. In this study, we investigated the possible miRNA changes and their effect of MTX on… read more here.
Keywords: like polarization; ube2d1 kat2b; macrophages ube2d1; hmgb1 ... See more keywords
C1QTNF3 is Upregulated During Subcutaneous Adipose Tissue Remodeling and Stimulates Macrophage Chemotaxis and M1-Like Polarization
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.914956
Abstract: The adipose tissue undergoes substantial tissue remodeling during weight gain-induced expansion as well as in response to the mechanical and immunological stresses from a growing tumor. We identified the C1q/TNF-related protein family member C1qtnf3 as… read more here.
Keywords: like polarization; c1qtnf3; adipose tissue; tissue remodeling ... See more keywords