Functionalized Collagen/Elastin‐like Polypeptide Hydrogels for Craniofacial Bone Regeneration
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202202477
Abstract: Critical‐sized cranial bone defects fail to re‐ossify and require the surgical intervention of cranioplasty. To achieve superior bone healing in such cases, a hydrogel consisting of an interpenetrating network of collagen and elastin‐like polypeptide to… read more here.
Keywords: like polypeptide; collagen elastin; bone; elastin like ... See more keywords
Effect of amino acid composition of elastin-like polypeptide nanoparticles on nonspecific protein adsorption, macrophage cell viability and phagocytosis.
Sign Up to like & getrecommendations! Published in 2021 at "Biopolymers"
DOI: 10.1002/bip.23468
Abstract: Development of elastin-like polypeptide (ELP) biomaterials is widespread, but information critical for clinical deployment is limited, with biocompatibility studies focused on a narrow cross-section of ELP sequences. Macrophages can impair biomaterial systems by degrading or… read more here.
Keywords: elp nps; amino acid; elp; elastin like ... See more keywords
Synthesis of single‐chain antibody fragment fused to the elastin‐like polypeptide in Nicotiana benthamiana and its application in affinity precipitation of difficult to produce proteins
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28158
Abstract: Plants are economical and sustainable factories for the production of recombinant proteins. Currently, numerous proteins produced using different plant‐based systems with applications as cosmetic and tissue culture ingredients, research and diagnostic reagents, and industrial enzymes… read more here.
Keywords: elp; elastin like; single chain; chain antibody ... See more keywords
Antibiofilm elastin-like polypeptide coatings: functionality, stability, and selectivity.
Sign Up to like & getrecommendations! Published in 2019 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2018.10.039
Abstract: Antimicrobial peptides (AMPs) are currently receiving interest as an alternative to conventional antibiotics to treat biomaterial-associated infection. However, the inherent instability of such peptides often limits their efficacy in intended clinical applications. Covalent immobilization of… read more here.
Keywords: antibiofilm elastin; polypeptide coatings; elastin like; coatings functionality ... See more keywords
Application of elastin-like polypeptide (ELP) containing extra-cellular matrix (ECM) binding ligands in regenerative medicine.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2022.03.018
Abstract: Extracellular matrix (ECM) molecules play an important role in regulating molecular signaling associated with proliferation, migration, differentiation, and tissue repair. The identification of new kinds of ECM mimic biomaterials to recapitulate critical functions of biological… read more here.
Keywords: medicine; matrix ecm; elp; elastin like ... See more keywords
A novel elastin‐like polypeptide drug carrier for cyclosporine A improves tear flow in a mouse model of Sjögren's syndrome
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Controlled Release"
DOI: 10.1016/j.jconrel.2018.10.026
Abstract: &NA; As a potent macrolide immunosuppressant, cyclosporine A (CsA) is used to treat multiple autoimmune diseases, including non‐autoimmune and autoimmune‐mediated dry eye disease, rheumatoid arthritis and psoriasis. Despite its potency, CsA has poor solubility, poor… read more here.
Keywords: gren syndrome; elastin like; model; like polypeptide ... See more keywords
Engineering Elastin-Like Polypeptide-Poly(ethylene glycol) Multiblock Physical Networks.
Sign Up to like & getrecommendations! Published in 2018 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.7b01424
Abstract: Hybrids of protein biopolymers and synthetic polymers are a promising new class of soft materials, as the advantages of each component can be complementary. A recombinant elastin-like polypeptide (ELP) was conjugated to poly(ethylene glycol) (PEG)… read more here.
Keywords: like polypeptide; poly ethylene; ethylene glycol; elastin like ... See more keywords
Thermosensitive Hybrid Elastin-like Polypeptide-Based ABC Triblock Hydrogel
Sign Up to like & getrecommendations! Published in 2020 at "Macromolecules"
DOI: 10.1021/acs.macromol.0c01744
Abstract: We report the synthesis of a well-defined hybrid ABC triblock terpolymer containing a synthetic poly(trimethylene carbonate) (PTMC) block A and a thermosensitive BC diblock of recombinant elastin-l... read more here.
Keywords: hybrid elastin; elastin like; like polypeptide; triblock ... See more keywords
Improvement of the Bonding Properties of Mineral Trioxide Aggregate by Elastin-Like Polypeptide Supplementation
Sign Up to like & getrecommendations! Published in 2019 at "Scanning"
DOI: 10.1155/2019/3484396
Abstract: Introduction Elastin-like polypeptide (ELP) supplementation was previously reported to enhance the physical properties of mineral trioxide aggregate (MTA). The aim of this study was to investigate the effect of ELP supplementation on the bonding properties… read more here.
Keywords: bonding properties; properties mineral; supplementation; mta ... See more keywords
Targeted elastin-like polypeptide fusion protein for near-infrared imaging of human and canine urothelial carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Oncotarget"
DOI: 10.18632/oncotarget.28271
Abstract: Cystoscopic visualization of bladder cancer is an essential method for initial bladder cancer detection and diagnosis, transurethral resection, and monitoring for recurrence. We sought to develop a new intravesical imaging agent that is more specific… read more here.
Keywords: canine; near infrared; elastin like; urothelial carcinoma ... See more keywords
Elastin-like Polypeptide Hydrogels for Tunable, Sustained Local Chemotherapy in Malignant Glioma
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14102072
Abstract: Glioblastoma (GBM) is a primary brain tumor that carries a dismal prognosis, which is primarily attributed to tumor recurrence after surgery and resistance to chemotherapy. Since the tumor recurrence appears near the site of surgical… read more here.
Keywords: elp; elp hydrogels; elastin like; gbm ... See more keywords