Label-Free and Homogenous Detection of Caspase-3-Like Proteases by Disrupting Homodimerization-Directed Bipartite Tetracysteine Display.
Sign Up to like & getrecommendations! Published in 2017 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.6b04771
Abstract: Caspase-3-like proteases (e.g., caspase-3 and caspase-7) constitute the core players of cell apoptosis, and their dysregulation has been linked to a number of human diseases, such as cancer and neurodegenerative disorders. However, the methods for… read more here.
Keywords: caspase; peptide; caspase like; bipartite tetracysteine ... See more keywords
The substrate selectivity of papain-like proteases from human-infecting coronaviruses correlates with innate immune suppression
Sign Up to like & getrecommendations! Published in 2023 at "Science Signaling"
DOI: 10.1126/scisignal.ade1985
Abstract: Coronaviruses that can infect humans can cause either common colds (HCoV-NL63, HCoV-229E, HCoV-HKU1, and HCoV-OC43) or severe respiratory symptoms (SARS-CoV-2, SARS-CoV, and MERS-CoV). The papain-like proteases (PLPs) of SARS-CoV, SARS-CoV-2, MERS-CoV, and HCoV-NL63 function in… read more here.
Keywords: like proteases; hcov; innate immune; papain like ... See more keywords
Papain-like and legumain-like proteases in rice: genome-wide identification, comprehensive gene feature characterization and expression analysis
Sign Up to like & getrecommendations! Published in 2018 at "BMC Plant Biology"
DOI: 10.1186/s12870-018-1298-1
Abstract: BackgroundPapain-like and legumain-like proteases are proteolytic enzymes which play key roles in plant development, senescence and defense. The activities of proteases in both families could be inhibited by a group of small proteins called cystatin.… read more here.
Keywords: seed; like legumain; expression; like proteases ... See more keywords