Chemical-induced chromatin remodeling reprograms mouse ESCs to totipotent-like stem cells.
Sign Up to like & getrecommendations! Published in 2022 at "Cell stem cell"
DOI: 10.1016/j.stem.2022.01.010
Abstract: Totipotent cells have more robust developmental potency than any other cell types, giving rise to both embryonic and extraembryonic tissues. Stable totipotent cell cultures and deciphering the principles of totipotency regulation would be invaluable to… read more here.
Keywords: totipotent like; like stem; stem cells; cell ... See more keywords
Wnt/BMP mediated metabolic reprogramming preserves multipotency of neural crest like stem cells.
Sign Up to like & getrecommendations! Published in 2023 at "Stem cells"
DOI: 10.1093/stmcls/sxad001
Abstract: Neural Crest-like Stem cells resembling embryonic neural crest cells (NCs) can be derived from adult human tissues such as the epidermis. However, these cells lose their multipotency rapidly in culture limiting their expansion for clinical… read more here.
Keywords: like stem; neural crest; crest like; stem cells ... See more keywords