A Combined α-Synuclein/Fibril (SynFib) Model of Parkinson-Like Synucleinopathy Targeting the Nigrostriatal Dopamine System
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DOI: 10.3233/jpd-223452
Abstract: Injections of pre-formed α-synuclein fibrils (PFFs) or overexpression of α-synuclein using AAV vectors are commonly used as models of Parkinson-like synucleinopathy in rats and mice. In the modified method reviewed here, the “SynFib” model, the… read more here.
Keywords: synfib model; parkinson like; dopamine; pathology ... See more keywords