Induced expression of GINS complex is an essential step for reactivation of quiescent stem-like tumor cells within the peri-necrotic niche in human glioblastoma
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-018-2797-z
Abstract: PurposeGlioblastoma is still intractable despite the progress in therapies, and the intractability is attributable to a minor population of stem-like tumor cells. As a niche harboring quiescent stem-like tumor cells with potentially high tumorigenicity, we… read more here.
Keywords: glioblastoma; like tumor; tumor cells; stem like ... See more keywords
Clear Cell Sarcoma-Like Tumor of the Gastrointestinal Tract
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DOI: 10.1007/s12029-018-0069-4
Abstract: Clear cell sarcoma-like tumor of the gastrointestinal tract (CCSLGT) is a relatively recently described neoplasm usually arising from wall of the small intestine [1–6]. Because of the rarity of CCSLGTas well as its overlapping histomorphologic… read more here.
Keywords: tumor gastrointestinal; like tumor; sarcoma like; cell sarcoma ... See more keywords
Infantile fibrosarcoma–like tumor driven by novel RBPMS-MET fusion consolidated with cabozantinib
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DOI: 10.1101/mcs.a005645
Abstract: Infantile fibrosarcoma (IFS) is nearly universally driven by gene fusions involving the NTRK family. ETV6-NTRK3 fusions account for ∼85% of alterations; the remainder are attributed to NTRK-variant fusions. Rarely, other genomic aberrations have been described… read more here.
Keywords: like tumor; novel rbpms; ifs like; fusion ... See more keywords
The shedded ectodomain of Lyve-1 expressed on M2-like tumor-associated macrophages inhibits melanoma cell proliferation
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DOI: 10.18632/oncotarget.21771
Abstract: Targeting immune cells that support tumor growth is an effective therapeutic strategy in tumor entities such as melanoma. M2-like tumor-associated macrophages (TAM) sustain tumor growth by secreting anti-inflammatory cytokines, proteases and growth factors. In this… read more here.
Keywords: melanoma cell; cell proliferation; like tumor; tumor ... See more keywords
Clear Cell Sarcoma-like Tumor of the Gastrointestinal Tract: Clinical Outcome and Pathologic Features of a Molecularly Characterized Tertiary Center Case Series.
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DOI: 10.21873/anticanres.12374
Abstract: BACKGROUND/AIM Clear cell sarcoma-like tumor of the gastrointestinal tract (CCSLTGT) is a very rare and relatively recently characterized mesenchymal neoplasm arising within the wall of the small bowel, stomach, or large bowel, predominantly in adolescents… read more here.
Keywords: gastrointestinal tract; tumor gastrointestinal; like tumor; sarcoma like ... See more keywords
Bortezomib Augments Natural Killer Cell Targeting of Stem-Like Tumor Cells
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DOI: 10.3390/cancers11010085
Abstract: Tumor cells harboring stem-like/cancer stem cell (CSC) properties have been identified and isolated from numerous hematological and solid malignancies. These stem-like tumor cells can persist following conventional cytoreductive therapies, such as chemotherapy and radiotherapy, thereby… read more here.
Keywords: like tumor; tumor cells; stem like; cell ... See more keywords